Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study

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Brief Title

Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study

Brief Summary

      Study of heterogeneity in associations between social deprivation and the initial
      presentation of 12 cardiovascular diseases.

Detailed Description

      This study is part of the CALIBER (Cardiovascular disease research using linked bespoke
      studies and electronic records) programme funded over 5 years from the NIHR and Wellcome
      Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia
      National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching
      aim of CALIBER is to better understand the aetiology and prognosis of specific coronary
      phenotypes across a range of causal domains, particularly where electronic records provide a
      contribution beyond traditional studies. CALIBER has received both Ethics approval (ref
      09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).

Study Type

Observational

Primary Outcome

Hazard ratios for the associations between social deprivation and initial presentation of 12 cardiovascular diseases.

Secondary Outcome

 Lifetime cumulative incidence per quintile of social deprivation

Condition

Abdominal Aortic Aneurysm

Intervention

No treatment

Study Arms / Comparison Groups

 No treatment
Description:

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Other

Estimated Enrollment

1937360

Start Date

January 2012

Completion Date

December 2014

Primary Completion Date

December 2013

Eligibility Criteria

        Inclusion Criteria:

          -  One year prior to study entry (up-to-standard follow-up, CPRD quality research
             standard).

          -  30 years or older

          -  Recorded sex

          -  Free of symptomatic CVD at inclusion.

        Exclusion Criteria:

          -  Pregnant women in the 6 months before the eligibility date

Gender

All

Ages

30 Years - N/A

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

, ,

Location Countries

United Kingdom

Location Countries

United Kingdom

Administrative Informations

NCT ID

NCT01937065

Organization ID

12_153R_IP4

Responsible Party

Principal Investigator

Study Sponsor

University College, London

Collaborators

 Wellcome Trust

Study Sponsor

, ,

Verification Date

September 2013