Brief Title
Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Brief Summary
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
Detailed Description
This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching aim of CALIBER is to better understand the aetiology and prognosis of specific coronary phenotypes across a range of causal domains, particularly where electronic records provide a contribution beyond traditional studies. CALIBER has received both Ethics approval (ref 09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).
Study Type
Observational
Primary Outcome
Hazard ratios for the associations between social deprivation and initial presentation of 12 cardiovascular diseases.
Secondary Outcome
Lifetime cumulative incidence per quintile of social deprivation
Condition
Abdominal Aortic Aneurysm
Intervention
No treatment
Study Arms / Comparison Groups
No treatment
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
1937360
Start Date
January 2012
Completion Date
December 2014
Primary Completion Date
December 2013
Eligibility Criteria
Inclusion Criteria: - One year prior to study entry (up-to-standard follow-up, CPRD quality research standard). - 30 years or older - Recorded sex - Free of symptomatic CVD at inclusion. Exclusion Criteria: - Pregnant women in the 6 months before the eligibility date
Gender
All
Ages
30 Years - N/A
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
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Location Countries
United Kingdom
Location Countries
United Kingdom
Administrative Informations
NCT ID
NCT01937065
Organization ID
12_153R_IP4
Responsible Party
Principal Investigator
Study Sponsor
University College, London
Collaborators
Wellcome Trust
Study Sponsor
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Verification Date
September 2013