Brief Title
AAA Rupture Risk Assessment in COVID-19 Pandemic
Official Title
Biomechanical Rupture Risk Assessment in Management of Patients With Abdominal Aortic Aneurysm in COVID-19 Pandemic
Brief Summary
The acute phase of the COVID-19 pandemic requires a redefinition of healthcare system to increase the number of available intensive care units for COVID-19 patients. This leads to the postponing of elective surgeries including the treatment of abdominal aortic aneurysm (AAA). The probabilistic rupture risk index (PRRI) recently showed its advantage over the diameter criterion in AAA rupture risk assessment. Its major improvement is in increased specificity and yet has the same sensitivity as the maximal diameter criterion. The objective of this study was to test the clinical applicability of the PRRI diagnostic method in a quasi-prospective observational patient cohort study.
Study Type
Observational
Primary Outcome
Test the clinical applicability of the BRRA method
Secondary Outcome
Reduction of time required for AAA assessment
Condition
Abdominal Aortic Aneurysm
Intervention
Biomechanical rupture risk assessment
Study Arms / Comparison Groups
BRRA group
Description: Rupture risk of asymptomatic AAAs in this group was estimated using Biomechanical rupture rist assessment (BRRA). BRRA considers an AAA as a pressure vessel and estimates its risk of rupture by comparing its wall stress to wall strength
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Diagnostic Test
Estimated Enrollment
102
Start Date
March 12, 2020
Completion Date
March 2022
Primary Completion Date
December 17, 2021
Eligibility Criteria
Inclusion Criteria: - presence of asymptomatic abdominal aortic aneurysm (AAA) - regular CT angiography scans available Exclusion Criteria: - rupture of AAA
Gender
All
Ages
N/A - N/A
Accepts Healthy Volunteers
No
Contacts
Robert Staffa, M.D., Ph.D., ,
Location Countries
Czechia
Location Countries
Czechia
Administrative Informations
NCT ID
NCT05197543
Organization ID
BRRA19
Responsible Party
Principal Investigator
Study Sponsor
Masaryk University
Collaborators
VSB - Technical University of Ostrava
Study Sponsor
Robert Staffa, M.D., Ph.D., Study Director, Masaryk University
Verification Date
January 2022