Preoperative Methylprednisolone in Endovascular Aortic Repair
Preoperative Methylprednisolone in Endovascular Aortic Repair - a Randomized Double Blind Placebo Controlled Clinical Trial
The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.
Systemic inflammatory response syndrome - SIRS
Length of postoperative hospital stay
Abdominal Aortic Aneurysms
Study Arms / Comparison Groups
Description: 75 patients will receive a single preoperative dosage of Methylprednisolone
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Primary Completion Date
Inclusion Criteria: - Elective endovascular repair of an asymptomatic abdominal aortic aneurysm. - Informed signed consent Exclusion Criteria: - Positive HIV status, positive hepatitis B or C status - Immunoinflammatory disease - except topically treated skin disease and respiratory disease. - Glaucoma - Gastric or duodenal ulcer - Systemic fungal infection - Immunosuppressive treatment - Current treatment for cancer - Allergy towards contents of Solu-Medrol - Alcohol consumption: Men > 21 drinks and women > 14 drinks weekly - Pregnancy - Lack of informed signed consent - Patients where follow up is planned at other location than Rigshospitalet.
18 Years - N/A
Accepts Healthy Volunteers
Louise de la Motte, MD, ,
EudraCT number 2009-013441-28
Louise de la Motte
Louise de la Motte, MD, Principal Investigator, Rigshospitalet, Denmark