Short-and Long-term Effects of a Home-based Rehabilitation Program in Patients With Bronchiectasis

Brief Title

Short-and Long-term Effects of a Home-based Rehabilitation Program in Patients With Bronchiectasis

Official Title

Short-and Long-term Effects of a Home-based Rehabilitation Program on Functional Capacity, Peripheral Muscle Strength and Quality of Life in Patients With Bronchiectasis: Randomized Controlled Trial

Brief Summary

      This study will investigate the short-and long-term effects of the home-based pulmonary
      rehabilitation on peripheral muscle strength, functional capacity and quality of life in
      patients with bronchiectasis. The participants will be randomized into two groups: control
      group (usual care and recommendations for practice exercise) and training group, that will
      perform aerobic (stepping training) and resistance training (lower and upper limbs) for eight
      weeks, three times a week. At baseline, immediately after finishing and after six months the
      patients will undergo assessments.
    

Detailed Description

      Home-based pulmonary rehabilitation (HBPR) has been used in patients with chronic obstructive
      pulmonary disease, asthma and pulmonary fibrosis. Results from HBPR have been similar to
      those observe in the outpatient pulmonary rehabilitation such improvement in exercise
      capacity, symptoms and quality of life. However, HBPR has not yet been investigated in
      patients with bronchiectasis, a progressive and debilitating disease with a high
      socioeconomic impact. Objective: To investigate the short-and long-term effects of the home
      rehabilitation program in peripheral muscle strength, functional capacity and quality of life
      in patients with bronchiectasis. Methods: Patients diagnosed with bronchiectasis will be
      recruited from the Obstructive Diseases Outpatient Clinic of the Hospital das Clínicas -
      Medicine School, University of São Paulo. Participants will be randomized into two groups:
      control group (usual care and recommendations for performing exercises and respiratory
      physiotherapy) and training group, that will perform aerobic (stepping training) and
      resistance training (lower and upper limbs) for eight weeks, three times a week. All patients
      will receive a phone call once a week and patients allocated to the training group,
      additionally, will get a home visit every 15 days. At baseline, immediately after finishing
      and after six months of the HBPR patients will undergo to assessments. Expected results: HBPR
      will have positive effects on exercise tolerance and quality of life. Also, this study will
      contribute to future guidelines on the recommendation of HBPR for patients with
      bronchiectasis.
    

Study Type

Interventional

Primary Outcome

Distance, in meters, performed in the Incremental Shuttle Walk Test

Secondary Outcome

 Time, in seconds, performed in the Endurance Shuttle Walk Test

Condition

Bronchiectasis

Intervention

Training Group

Study Arms / Comparison Groups

 Training Group

Description:  Patients with bronchiectasis in home-based pulmonary rehabilitation

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Status

Other

Estimated Enrollment

66

Start Date

June 2016

Completion Date

August 2019

Primary Completion Date

August 2019

Eligibility Criteria

        Inclusion Criteria:

        Clinical diagnosis and/or tomographic bronchiectasis Clinically stable (no change in
        symptoms of dyspnea, in the amount and color of the secretion) Have completed the
        outpatient pulmonary rehabilitation for more than a year Not engaged in a regular physical
        activity.

        Exclusion Criteria:

        Smokers With other lung related diseases (asthma, COPD and cystic fibrosis) Severe
        cardiovascular diseases Musculoskeletal limitation Unable to perform the tests and the
        training protocol due desaturation (pulse oxygen saturation ≤ 80%) over the recommended
        exercise intensity.
      

Gender

All

Ages

18 Years - 80 Years

Accepts Healthy Volunteers

No

Contacts

Simone Dal Corso, PT, PhD, , 

Location Countries

Brazil

Location Countries

Brazil

NCT ID

NCT02731482

Organization ID

Bronchiectasis Rehabilitation

Responsible Party

Principal Investigator

Study Sponsor

University of Nove de Julho

Collaborators

 University of Sao Paulo

Study Sponsor

Simone Dal Corso, PT, PhD, Study Director, University of Nove de Julho

Verification Date

August 2019