Brief Title
Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis
Official Title
Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis in a North-American Tertiary Center at the Beginning of the 21st Century
Brief Summary
The study consist of a retrospective analysis of the etiologies, investigations and outcomes
of patients presenting between 2005 to 2010 with hemoptysis in a North-American Tertiary
center.
Detailed Description
RATIONALE:
Hemoptysis, mild or massive, is worrisome for both patients and physicians. The management is
different depending on the causes, which are not well defined for the North American
population. Despite the fact that this symptom is commonly reported in clinic, there are only
a few studies published on this subject in the North-American population. Tuberculosis was a
frequent cause of hemoptysis described in populations overseas, which seems less prevalent in
the investigators center.
Also, there are no known official guidelines regarding the investigation and management of
hemoptysis. The investigators hypothesized that the use of modern technology in a North
American population may result in different findings and provide a more accurate diagnostic
approach.
Therefore, the study compares the different etiologies of hemoptysis and investigation
modalities used in patients presenting in a North-American tertiary center.
METHOD:
The investigators did a retrospective analysis of medical chart from patients with hemoptysis
who visited the investigators center between 2005 and 2010. Each visit has been reviewed
individually to describe the characteristics of patients, etiologies of hemoptysis and
investigation modalities used. All-cause mortality at 2 years was also recorded.
Descriptive statistical analyses will conducted on the data available.
Study Type
Observational
Primary Outcome
Etiologies of hemoptysis
Secondary Outcome
Sensitivity of chest X-ray, chest CT-scan and CT-angiography, bronchoscopy, ventilation-perfusion with single-photon emission computed tomography and pulmonary angiography.
Condition
Hemoptysis
Study Arms / Comparison Groups
Patients presenting with hemoptysis
Description: Patients over 18 years of age presenting with hemoptysis at the Centre Hospitalier Universitaire de Sherbrooke (CHUS) between the periods of 2005 to 2010.
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
1000
Start Date
October 2012
Completion Date
June 2017
Primary Completion Date
June 2017
Eligibility Criteria
Inclusion Criteria:
Any patient over the age of 18 presenting with:
- A diagnosis of hemoptysis on an outpatient basis.
- A diagnosis of hemoptysis during consultation in the emergency department.
- A diagnosis of hemoptysis on the admission sheet.
- A diagnosis of hemoptysis when hospitalized.
- A complication of hemoptysis
- Hemoptysis on the report of the bronchoscopy, chest computed tomography, pulmonary
angiography, ventilation-perfusion single-photon emission computed tomography or blood
transfusion.
Exclusion Criteria:
- Patients under 18 years of age.
- Patient who refused investigation for hemoptysis.
- Incomplete medical chart
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
Brian Grodin-Beaudoin, MD, 18193461110, [email protected]
Location Countries
Canada
Location Countries
Canada
Administrative Informations
NCT ID
NCT02913365
Organization ID
12-099
Responsible Party
Principal Investigator
Study Sponsor
Université de Sherbrooke
Study Sponsor
Brian Grodin-Beaudoin, MD, Principal Investigator, Université de Sherbrooke
Verification Date
September 2016