Comparison of Sit-to-stand Test With Six-minute Walk Test in Bronchiectasis and Healthy Children

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Brief Title

Comparison of Sit-to-stand Test With Six-minute Walk Test in Bronchiectasis and Healthy Children

Official Title

Comparison of Sit-to-stand Test With Six-minute Walk Test in Bronchiectasis and Healthy Children

Brief Summary

      Children with bronchiectasis and age-matched healthy controls will be evaluated with
      sit-to-stand test and six-minute walk test and utilization of STST in determining functional
      capacity will be investigated.
    

Detailed Description

      Bronchiectasis (BE) is a chronic condition which is characterized by the permanent abnormal
      widening of the bronchi as a result of repetitive airway infections and inflammation.
      Disabling cough and shortness of breath, excess mucus production, progressive airway
      obstruction and loss of skeletal muscle mass are the primary factors that impairs exercise
      tolerance in BE patients. Imaging modalities and pulmonary function test are insufficient to
      determine disease burden or the prognosis thus it is stated that exercise tolerance and
      quality of life should also be evaluated in these patients.

      Exercise tolerance can be evaluated using cardiopulmonary exercise test by directly measuring
      oxygen consumption but the field tests such as six-minute walk test (6MWT), shuttle walk test
      or stair climbing tests also provides reliable data on exercise tolerance by measuring
      functional capacity. Among field tests, 6MWT is the most commonly used test for evaluating
      functional capacity in cardiopulmonary patients. Although 6MWT is easy to apply and does not
      require any special equipment, it still requires a 30-m long corridor and a total testing
      time of approx. 20 minutes considering the pre- and post-test resting periods which may
      impair its feasibility in some clinical settings.

      Sit-to-stand test (STST) is firstly developed for older population to measure mobility
      related function and physical performance. Today, it is widely used in various populations
      including cardiopulmonary diseases such as cystic fibrosis, chronic obstructive pulmonary
      disease and heart failure. The investigator's aim in this study is to investigate whether
      STST is utilizable for evaluating functional capacity in children with BE.
    


Study Type

Observational


Primary Outcome

Six-minute walk test distance

Secondary Outcome

 Number of repetitions in sit-to-stand test

Condition

Bronchiectasis

Intervention

Measurement of functional capacity

Study Arms / Comparison Groups

 Bronchiectasis
Description:  Children with bronchiectasis

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

80

Start Date

December 23, 2019

Completion Date

January 30, 2020

Primary Completion Date

January 30, 2020

Eligibility Criteria

        Inclusion Criteria:

          -  Diagnosis of non-cystic fibrosis bronchiectasis

        Exclusion Criteria:

          -  Hospitalization history in past month

          -  Diagnosis of other chronic pediatric diseases which may impair exercise tolerance such
             as cerebral palsy or neuromuscular disease

          -  Candidates for lung transplantation or history of lung transplantation
      

Gender

All

Ages

6 Years - 18 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

, , 

Location Countries

Turkey

Location Countries

Turkey

Administrative Informations


NCT ID

NCT04153448

Organization ID

bvumzeren04


Responsible Party

Principal Investigator

Study Sponsor

Bezmialem Vakif University


Study Sponsor

, , 


Verification Date

January 2020