Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis

Brief Title

Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis

Official Title

Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis

Brief Summary

      The effect of comprehensive respiratory physiotherapy applications on respiratory function,
      functional capacity and peripheral muscle strength in children with cystic fibrosis and
      non-cystic fibrosis will be compared.
    

Detailed Description

      Bronchiectasis may be a congenital cause such as cystic fibrosis (CF) or non-cystic fibrosis
      such as primary ciliary dyskinesia, post-infectious conditions, aspiration and
      immunodeficiency; It is a disease characterized by irreversible dilatation of airways.
      Symptoms; purulent sputum production, chronic cough, hemoptysis, recurrent fever and
      pleurisy. Mucociliary clearance disorder secondary to inflammation and involvement of
      exocrine glands in CF plays a major role in the development of symptoms; In non-cystic
      fibrosis bronchiectasis (NCFB), the development of similar symptoms may occur regardless of
      these reasons. However, in the examinations of CF, proximal airways; In NCFB, distal airways
      have been affected more intensively. As part of pulmonary rehabilitation, comprehensive
      respiratory physiotherapy (CRP) has an important role in the treatment and management of
      bronchiectasis. Airway cleaning techniques, approaches to reducing respiratory work, and
      patient education form the basis of CRP and play an active role in the treatment and
      management of the disease. In the literature, there are studies in which the effects of CRP
      are given in both CF and NCFB patients and studies comparing evaluation results in both
      groups without treatment. However, no study was found to compare the efficacy of CRP in these
      two groups of diseases. Therefore, in this study, the investigators aimed to investigate the
      differences between the efficacy of CRP among the groups in children with CF and NCFB.
    

Study Type

Interventional

Primary Outcome

Forced Vital Capacity (FVC)

Condition

Cystic Fibrosis

Intervention

Comprehensive Respiratory Physiotherapy

Study Arms / Comparison Groups

 Cystic Fibrosis

Description:  Children with cystic fibrosis

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Status

Other

Estimated Enrollment

40

Start Date

January 1, 2020

Completion Date

December 30, 2020

Primary Completion Date

December 30, 2020

Eligibility Criteria

        Inclusion Criteria:

          -  Being between 6-18 years old

          -  Clinically diagnosed as cystic fibrosis or non-cystic fibrosis bronchiectasis

        Exclusion Criteria:

          -  Previous history of lung or liver transplantation

          -  Have had an acute exacerbation in the last month and / or have a history of
             hospitalization

          -  Having a diagnosis of orthopedic problems affecting mobility or a history of
             musculoskelatal surgery
      

Gender

All

Ages

6 Years - 18 Years

Accepts Healthy Volunteers

No

Contacts

, +902125232288, [email protected]

Location Countries

Turkey

Location Countries

Turkey

NCT ID

NCT04170114

Organization ID

bvuhucgun02

Responsible Party

Sponsor

Study Sponsor

Bezmialem Vakif University

Study Sponsor

, , 

Verification Date

May 2020