Brief Title
Severe Aortic Stenosis in Patients Referred for Valve Surgery
Official Title
A Prospective Longitudinal Study of Severe Aortic Stenosis in Elderly and Outcome of Aortic Surgery.
Brief Summary
Our main hypothesis on the present study is that new parameters such as risk-taking behavior, patients motivation, health related quality of life, new biomarkers and more precise echocardiography measures in addition to traditional parameters will improve pre-operative risk assessment in patients with AS and better guide patients and doctors in decision whether to operate or not.
Detailed Description
Patients referred for surgery are included thorough reading referral letter. Data collected in the study wil be compared with data from Medical records and clinical examination. Data entered will be controlled by two investigators. Data wil be compared to national norms and from result of other studies.
Study Type
Observational [Patient Registry]
Primary Outcome
Death due cardiovascular events
Secondary Outcome
MACE ( Major cardiovascular events )
Condition
Aortic Stenosis
Study Arms / Comparison Groups
Elderly with severe aortic stenosis
Description: Patients with severe symptomatic aortic stenosis referred for consideration of surgical aortic valve replacement
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
500
Start Date
February 2010
Completion Date
June 2014
Primary Completion Date
April 2014
Eligibility Criteria
Inclusion Criteria: - Patients above 18 years with symptomatic AS referred to preoperative examination. Exclusion Criteria: - Exclusion: Patients who do not want to participate. Patients not able to speak and read Norwegian.
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
Kjell I Pettersen, MD, 0047 98043412, [email protected]
Location Countries
Norway
Location Countries
Norway
Administrative Informations
NCT ID
NCT01794832
Organization ID
SAS
Responsible Party
Principal Investigator
Study Sponsor
Oslo University Hospital
Study Sponsor
Kjell I Pettersen, MD, Study Director, University of Oslo
Verification Date
April 2014