Brief Title
Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis
Official Title
Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis
Brief Summary
Aortic valve pathology is the third most common cardiovascular disease after coronary artery disease and hypertension, which is responsible for severe morbidity and mortality in elderly patients and requires surgical treatment in its most severe form of progression. The purpose of this study is to find a link between arterial stiffness and degenerative aortic stenosis. If this link is established, arterial stiffness may become a medical therapeutic target in order to delay the evolution of the disease.
Study Type
Interventional
Primary Outcome
Analysis of echocardiographic measurements of possible differences between average VOP and Sao i in terms of RA severities
Condition
Pulse Wave
Intervention
Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction
Study Arms / Comparison Groups
Control group of 150 heart disease-free individuals
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
900
Start Date
July 3, 2017
Completion Date
June 20, 2027
Primary Completion Date
June 20, 2027
Eligibility Criteria
Inclusion Criteria: - Patients over 18 years of age, without legal protection (guardianship or curatorship), - Stable hemodynamic status. - Affiliation to a social security scheme Exclusion Criteria: - Hemodynamically unstable patients: Systolic PA <10 cmHg, rapid peripheral pulse and spinning, mottling, obnubilation, oliguria, sweating, coma - History of significant valvulopathy other than an aortic stenosis, - Pregnancy. - Patient under tutelage or curatelle or deprived of public right.
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
, +33322455885, [email protected]
Location Countries
France
Location Countries
France
Administrative Informations
NCT ID
NCT03140735
Organization ID
PI2016_843_0035
Responsible Party
Sponsor
Study Sponsor
Centre Hospitalier Universitaire, Amiens
Study Sponsor
, ,
Verification Date
August 2018