Brief Title
On Dose Efficiency of Modern CT-scanners in Chest Scans
Official Title
On Dose Efficiency of Modern CT-scanners in Chest Scans- a Prospective, Randomized Study
Brief Summary
CT scans of the chest / thorax are of great importance both in the initial diagnosis and in the follow-up of pulmonary or thoracic diseases. As an example, CT angiography of the pulmonary arteries (CTPA) is worldwide considered to be gold standard test in patients with a suspicion for pulmonary embolism. The aim of this study is to measure and compare dose efficiency of modern CT scanners for unenhanced and contrast-enhanced scan protocols of the chest/thorax. Patients who are referred for a CT of the chest/thorax will be randomly assigned to one of the three CT scanners currently in use at our institution.
Study Type
Interventional
Primary Outcome
Parameters of Objective Image Quality
Secondary Outcome
Subjective Image Quality Evaluation (entire cohort and for individual disease groups)
Condition
Pneumonia
Intervention
Imaging on Scanner with Spectral Imaging Capabilities
Study Arms / Comparison Groups
Scanner 1
Description: Imaging performed on scanner 1: Photon-Counting Detector CT
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Diagnostic Test
Estimated Enrollment
2400
Start Date
October 7, 2021
Completion Date
October 6, 2024
Primary Completion Date
October 6, 2023
Eligibility Criteria
Inclusion Criteria: - patient is referred for an unenhanced CT OR contrast-enhanced CT of the chest/thorax confirmed by a board-certified radiologist ('justifying indication' according to German/European radiation protection law) AND - patient is at least 18 years of age AND - patient (is able to give informed consent and) has given informed consent. Exclusion Criteria: - high degree of medical urgency (i.e. patient cannot be consented for iv contrast according to routine procedures) - known or suspected pregnancy, or lactating . contraindications for contrast agent (renal failure, allergy, hyperthyroidism)
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
Florian Schwarz, MD, +498214002441, [email protected]
Location Countries
Germany
Location Countries
Germany
Administrative Informations
NCT ID
NCT04996693
Organization ID
21-0368
Responsible Party
Sponsor
Study Sponsor
University Hospital Augsburg
Study Sponsor
Florian Schwarz, MD, Principal Investigator, Universitaetsklinikum Augsburg
Verification Date
March 2022