Brief Title
China Valve Registry Study-1
Official Title
Registry Study of Aortic Valve Diseases in Chinese Elderly
Brief Summary
With the aging of Chinese population, degenerative valvular disease is becoming more and more frequent, which has brought a heavy burden to our society. Taking aortic stenosis (AS) as an example, the incidence of AS in population over the age of 65 are about 2%, and in population above the age of 85 can be amounted to 4-8%, in the Western country. Since the invention of transcatheter aortic valve replacement (TAVR),aortic valve disease (AVD),including AS and aortic regurgitation (AR), has attracted more and more attention. To date, there are few data about the prevalence of AVD in China. The characteristics and prognosis of AVD in China are still unknown. Therefore, the investigators design a prospective, observational cohort study to investigate characteristics, treatments and prognosis of AVD in Chinese elderly population. The results of the study will provide a basis for the future national health policy for prevention and treatment of AVD in the elderly.
Study Type
Observational [Patient Registry]
Primary Outcome
Cardiovascular (CV) death or hospitalization for heart failure (HF)
Secondary Outcome
Number of all-cause mortality
Condition
Aortic Valve Disease
Study Arms / Comparison Groups
AS group
Description: Severe AS patients, without severe AR
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
2000
Start Date
May 2016
Completion Date
May 2020
Primary Completion Date
May 2018
Eligibility Criteria
Inclusion Criteria: - Severe AS or AR indicated by echocardiography ; - 60 years old or older. Exclusion Criteria: - Having both Severe AR and Severe AS; - Having underwent surgical or transcatheter treatment for AVD; - Non-degenerative AVD.
Gender
All
Ages
60 Years - N/A
Accepts Healthy Volunteers
No
Contacts
, , [email protected]
Administrative Informations
NCT ID
NCT02623907
Organization ID
CHIVAS2015
Responsible Party
Sponsor
Study Sponsor
Shanghai Zhongshan Hospital
Study Sponsor
, ,
Verification Date
December 2015