Brief Title
Vestibular Function After Chemoradiotherapy for Nasopharyngeal Carcinoma
Official Title
Vestibular Function After Chemoradiotherapy for Nasopharyngeal Carcinoma
Brief Summary
Nasopharyngeal carcinoma (NPC) is usually treated with chemoradiotherapy. While the effects of this treatment on cochlear function is well characterized, its effect on vestibular function is not well studied. In this study the investigators will study the vestibular function of 50 patients undergoing chemoradiotherapy for NPC both before and after treatment in order to better define its effects. All patients will undergo a validated questionnaire (dizziness handicap index), posturography, audiometry and vestibular-evoked myogenic potentials.
Study Type
Observational
Primary Outcome
Subjective dizziness and vestibular dysfunction using the dizziness handicap index
Condition
Nasopharyngeal Carcinoma
Intervention
Chemoradiotherapy for nasopharyngeal carcinoma
Study Arms / Comparison Groups
Study group
Description: Patients older than 18 who are planned to undergo chemoradiotherapy for nasopharyngeal carcinoma.
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Radiation
Estimated Enrollment
50
Start Date
August 2016
Primary Completion Date
December 2016
Eligibility Criteria
Inclusion Criteria: - Age 18 years or older. - Biopsy-proven NPC. - About to undergo chemoradiotherapy with intensity-modulated radiotherapy (IMRT). Exclusion Criteria: - Pregnancy. - Prior vestibular dysfunction.
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
, +972-3-9376458, [email protected]
Location Countries
Israel
Location Countries
Israel
Administrative Informations
NCT ID
NCT02505672
Organization ID
0361-14-RMC
Responsible Party
Principal Investigator
Study Sponsor
Rabin Medical Center
Study Sponsor
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Verification Date
April 2016