Brief Title
Radiation Plus Concurrent Nimotuzumab in Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Brief Summary
Radiation Plus Concurrent Nimotuzumab in Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Detailed Description
Elderly patients with locoregionally advanced nasopharyngeal carcinoma were given an initial dose of nimotuzumab (200 mg) 7days before receiving concurrent radiotherapy, weekly nimotuzumab (200 mg/week).
Study Phase
Phase 2
Study Type
Interventional
Primary Outcome
Toxicity was graded according to the National Cancer Institute-Common Toxicity Criteria for Adverse Events version 3.0.
Condition
Nasopharyngeal Carcinoma
Intervention
Nimotuzumab
Study Arms / Comparison Groups
Nimotuzumab
Description: Elderly patients with locoregionally advanced nasopharyngeal carcinoma were given an initial dose of nimotuzumab (200 mg) 7days before receiving concurrent radiotherapy, weekly nimotuzumab (200 mg/week).
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Drug
Estimated Enrollment
30
Start Date
January 2017
Completion Date
December 2019
Primary Completion Date
December 2019
Eligibility Criteria
Inclusion Criteria: - Previously untreated and histologically confirmed locoregionally advanced nasopharyngeal carcinoma Exclusion Criteria: - A history of another invasive cancer, prior RT to the head and neck area, prior cytotoxic chemotherapy or anti-EGFR therapy or the presence of any serious medical conditions, supposed to live less than 6 months.
Gender
All
Ages
65 Years - N/A
Accepts Healthy Volunteers
No
Contacts
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Location Countries
China
Location Countries
China
Administrative Informations
NCT ID
NCT03025958
Organization ID
ZJCH-2016-HN04
Responsible Party
Sponsor
Study Sponsor
Zhejiang Cancer Hospital
Study Sponsor
, ,
Verification Date
January 2017