Superselective Intra-arterial Chemotherapy Treatment for Retinoblastoma- 5 Year Results From Turkey

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Brief Title

Superselective Intra-arterial Chemotherapy Treatment for Retinoblastoma- 5 Year Results From Turkey

Official Title

Superselective Intra-arterial Chemotherapy Treatment for Retinoblastoma- 5 Year Results From Turkey

Brief Summary

      Retrospective review of 5-year long term outcomes of superselective intra-arterial
      chemotherapy treatment in retinoblastoma in a single institute.

      The treatment outcomes, globe salvage rates and complications of superselective
      intra-arterial chemotherapy both for treating naive patients (primary treatment group) and
      for patients who received systemic chemotherapy previously (secondary treatment group) were
      evaluated.

Study Type

Observational

Primary Outcome

globe salvage

Condition

Retinoblastoma

Intervention

intra-arterial administration of melphalan

Study Arms / Comparison Groups

 group 1
Description:  Patients who received intra-arterial chemotherapy as a first line treatment

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Drug

Estimated Enrollment

30

Start Date

August 30, 2016

Completion Date

November 30, 2016

Primary Completion Date

November 30, 2016

Eligibility Criteria

        Inclusion Criteria:

          -  patients diagnosed with unilateral/bilateral retinoblastoma

        Exclusion Criteria:

          -  patients with trilateral retinoblastoma

          -  extraoculer involvement

          -  patients with blood dyscrasias, bleeding and clotting disorders

Gender

All

Ages

5 Months - 7 Years

Contacts

, ,

Location Countries

Turkey

Location Countries

Turkey

Administrative Informations

NCT ID

NCT03935074

Organization ID

10136532

Responsible Party

Principal Investigator

Study Sponsor

Istanbul University-Cerrahpasa

Study Sponsor

, ,

Verification Date

May 2019