Brief Title
Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study
Official Title
Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study
Brief Summary
This study evaluate the effect of dexmedetomidine on intelligence test in pediatric patients with multiple anesthesia exposure. Children who are diagnosed with retinoblastoma and receive first exam under general anesthesia before age of 2 are included. Intelligence test will performed when patients' age are 4.
Study Type
Interventional
Primary Outcome
IQ score at age of 4
Condition
Retinoblastoma
Intervention
Dexmedetomidine
Study Arms / Comparison Groups
Control group
Description: Children diagnosed with retinoblastoma and received exam under anesthesia (EUA) before the age of 30 months, and is not yet 4 years old Children who are undergoing exams and treatment such as EUA, chemoport insertion, or intra-arterial chemotherapy under general anesthesia Sevoflurane is used only for anesthesia
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Drug
Estimated Enrollment
60
Start Date
February 5, 2021
Completion Date
February 20, 2025
Primary Completion Date
January 20, 2025
Eligibility Criteria
Inclusion Criteria: - Patients who are first diagnosed as retinoblastoma and scheduled for EUA and treatment under general anesthesia before age of 2 Exclusion Criteria: -
Gender
All
Ages
N/A - 2 Years
Accepts Healthy Volunteers
No
Contacts
, 01076658848, [email protected]
Location Countries
Korea, Republic of
Location Countries
Korea, Republic of
Administrative Informations
NCT ID
NCT04700514
Organization ID
2009-039-1155
Responsible Party
Principal Investigator
Study Sponsor
Seoul National University Hospital
Study Sponsor
, ,
Verification Date
November 2021