Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure – Preliminary Study

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Brief Title

Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study

Official Title

Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study

Brief Summary

      This study evaluate the effect of dexmedetomidine on intelligence test in pediatric patients
      with multiple anesthesia exposure. Children who are diagnosed with retinoblastoma and receive
      first exam under general anesthesia before age of 2 are included. Intelligence test will
      performed when patients' age are 4.

Study Type

Interventional

Primary Outcome

IQ score at age of 4

Condition

Retinoblastoma

Intervention

Dexmedetomidine

Study Arms / Comparison Groups

 Control group
Description:  Children diagnosed with retinoblastoma and received exam under anesthesia (EUA) before the age of 30 months, and is not yet 4 years old
Children who are undergoing exams and treatment such as EUA, chemoport insertion, or intra-arterial chemotherapy under general anesthesia
Sevoflurane is used only for anesthesia

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Drug

Estimated Enrollment

60

Start Date

February 5, 2021

Completion Date

February 20, 2025

Primary Completion Date

January 20, 2025

Eligibility Criteria

        Inclusion Criteria:

          -  Patients who are first diagnosed as retinoblastoma and scheduled for EUA and treatment
             under general anesthesia before age of 2

        Exclusion Criteria:

        -

Gender

All

Ages

N/A - 2 Years

Accepts Healthy Volunteers

No

Contacts

, 01076658848, [email protected]

Location Countries

Korea, Republic of

Location Countries

Korea, Republic of

Administrative Informations

NCT ID

NCT04700514

Organization ID

2009-039-1155

Responsible Party

Principal Investigator

Study Sponsor

Seoul National University Hospital

Study Sponsor

, ,

Verification Date

November 2021