Brief Title
Validation and Reliability of the CHO-KLAT in Turkish
Official Title
Validation and Reliability of the Canadian Haemophilia Outcomes-Kids' Life Assessment Tool (CHO-KLAT) in Turkish
Brief Summary
The aim of this study is to investigate the Turkish validity and reliability of the Canadian Haemophilia Outcomes-Kids' Life Assessment Tool version2.0. Patients aged 4-18 years with hemophilia a or b will be included in the study. The study was planned as a multicenter and it is aimed to reach 100 patients. The process included four steps: a linguistic adaptation, cognitive debriefing interviews with children and their parents, a validity assessment with the Pediatric Quality of Life Inventory (PedsQL) as a comparator, and a test retest reliability assessment.
Detailed Description
Health-related quality of life assessment is considered an important outcome in the evaluation of children with hemophilia. The Canadian Haemophilia Outcomes-Kids' Life Assessment Tool version2.0 is a disease-specific health-related quality of life measurement tool for 4 to 18-year-old boys with haemophilia. The aim of this study is to ensure the use of CHO-KLAT in clinical studies in Turkey. Methods: Patients aged 4-18 years with hemophilia a or b will be included in the study.The study will be carried out in Van, Gaziantep and Adana provinces in Turkey and and it is aimed to reach 100 patients with hemophilia. The process included four steps: a linguistic adaptation, cognitive debriefing interviews with children and their parents, a validity assessment with the Pediatric Quality of Life Inventory (PedsQL) as a comparator, and a test retest reliability assessment.
Study Type
Interventional
Primary Outcome
HRQoL questionnaire
Condition
Hemophilia A
Intervention
Evaluation of health related quality of life
Study Arms / Comparison Groups
Hemophilia
Description: Evaluation of quality of life of children with hemophilia in Turkey
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
100
Start Date
June 1, 2022
Completion Date
December 1, 2022
Primary Completion Date
September 1, 2022
Eligibility Criteria
Inclusion Criteria: - have Hemophilia A or B Exclusion Criteria: - Did not have significant cognitive impairment
Gender
Male
Ages
4 Years - 18 Years
Accepts Healthy Volunteers
No
Contacts
Ayse Merve Tat, Asst.Prof, +905052431112, [email protected]
Location Countries
Turkey
Location Countries
Turkey
Administrative Informations
NCT ID
NCT05439642
Organization ID
YuzuncuYıl2022/1
Responsible Party
Principal Investigator
Study Sponsor
Yuzuncu Yıl University
Collaborators
Hasan Kalyoncu University
Study Sponsor
Ayse Merve Tat, Asst.Prof, Study Director, Van Yuzuncu Yıl University Faculty of Health Sciences
Verification Date
June 2022