Brief Title
Osteoporosis and Haemophilia
Official Title
Osteoporosis Screening in Adult Patients With Haemophilia and Influence of Physical Activity on the Prevalence of Osteoporosis
Brief Summary
The aim of this study is to evaluate the prevalence of osteoporosis in adult patients with haemophilia.
Detailed Description
The aim of this study is to evaluate the prevalence of osteoporosis in adult patients with haemophilia. Subsequently, the ascertained prevalence of osteoporosis in patients with haemophilia will be compared to the latest published data of osteoporosis in Germany. Furthermore, the impact of severity of haemophilia, comorbidities as well as the role of both physical activity and individual joint condition as influencing factors on the presence of osteoporosis will be analysed by this study.
Study Type
Observational
Primary Outcome
bone mass/bone density maesurement
Secondary Outcome
haemophilia related clinical data
Condition
Osteoporosis
Study Arms / Comparison Groups
Patients with mild haemophilia A or B
Description: (FVIII or IX >5 %, ≥ 18 years' old)
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
150
Start Date
August 19, 2020
Completion Date
November 1, 2022
Primary Completion Date
November 1, 2022
Eligibility Criteria
Inclusion Criteria: - Adult patients (≥ 18 years of age) suffering from mild (FVIII or IX >5 %), moderate (FVIII or IX 1-5 %) or severe (FVIII or IX <1 %) haemophilia A or B - Submitted written consent to participate in the study Exclusion Criteria: - Patients suffering from other bleeding diseases - PWH without written consent - PWH < 18 years of age - Secondary osteoporosis
Gender
Male
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
Andreas Strauß, PD Dr., 004922828714176, [email protected]
Location Countries
Germany
Location Countries
Germany
Administrative Informations
NCT ID
NCT04524481
Organization ID
NISOSTEO20200529
Secondary IDs
2020-003072-41
Responsible Party
Sponsor-Investigator
Study Sponsor
PD Dr. Andreas Strauß
Collaborators
Bayer
Study Sponsor
Andreas Strauß, PD Dr., Principal Investigator, Medicine of the University of Bonn
Verification Date
September 2020