Margin Status After Pancreaticoduodenectomy for Cancer
Margin Status After Pancreaticoduodenectomy for Cancer. Results of a Multicentric Prospective Randomized Trial
This multicentric prospective randomized controlled trial (RCT) compares the Leeds Pathology Protocol (LEEPP) with other "conventional" pathological protocol of PD specimen for periampullary cancer. Our aims were to evaluate the impact of the protocol and of the clearance on R1 rate and its prognostic value.
R1 resection rate
Leeds Pathology Protocol (LEEPP)
Study Arms / Comparison Groups
Description: Leeds Pathology Protocol (LEEPP)
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Primary Completion Date
Inclusion Criteria: - pancreaticoduodenectomy for periampullary cancer Exclusion Criteria: - diagnosis of neuroendocrine neoplasm; - previous pancreatic surgery; - frozen section of each transection margins not performed or presence of positive transection margins without further resection (R1 intraoperative resection); - presence of macroscopic residual tumor (R2 resection).
18 Years - N/A
Accepts Healthy Volunteers
Campus Bio-Medico University
Humanitas Hospital, Italy