Combined HCC-MFCCC

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Bile duct cancer
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Brief Title

Combined HCC-MFCCC

Official Title

Survival After Hepatectomy for Combined Hepatocellular Cholagiocarcinoma

Brief Summary

      Combined hepatocellular and mass-forming cholangiocarcinoma (cHCC-MFCCC) is a rare tumor. The
      aim of this study was the analysis of the outcome comparing such tumor with classic
      hepatocellular carcinoma (HCC) and mass-forming cholangiocarcinoma (MFCCC).

Detailed Description

      The institutional prospectively maintained database was queried, and 20 patients with
      cHCC-MFCCC were identified. A 2:1 match was performed with 40 patients operated in the same
      period for HCC, and with 40 operated for MFCCC. Only T1 or T2 patients N0 M0 were considered.
      Primary endpoint was the overall survival (OS) and disease-free survival (DFS).

Study Type

Observational

Primary Outcome

Survival analysis

Condition

Liver Carcinoma

Intervention

Hepatectomy

Study Arms / Comparison Groups

 cHCC-MFCCC
Description:  Patients affected by combined HCC-MFCCC

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Procedure

Estimated Enrollment

100

Start Date

January 1, 2004

Completion Date

May 15, 2017

Primary Completion Date

December 31, 2014

Eligibility Criteria

        Inclusion Criteria:

          -  positive histology for cHCC-MFCCC, HCC, and MFCCC

          -  complete clinical, surgical, pathological and follow-up data.

        Exclusion Criteria:

          -  patients preoperatively treated with chemotherapy, radiofrequency ablation or
             trans-arterial therapies were excluded.

          -  patients operated for recurrent disease and/or with non-radical surgery

          -  patients with missing data were also excluded

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

No

Contacts

, ,

Administrative Informations

NCT ID

NCT03178409

Organization ID

cHCC-MFCCC

Responsible Party

Principal Investigator

Study Sponsor

University of Milan

Study Sponsor

, ,

Verification Date

June 2017