Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Prospective Study on the Comparison Between the Clinicopathological Outcomes According to the Methods of Preoperative Biliary Drainage in Periampullary Cancers Causing Obstructive Jaundice
Preoperative biliary drainage methods include percutaneous transhepatic biliary drainage (PTBD), endoscopic nasobiliary drainage (ENBD), and endoscopic retrograde biliary drainage (ERBD). Endoscopic biliary drainages often induce peritumoral inflammation and it increase difficulties in determining a proper resection margin. The purpose of this study is to compare the clinicopathological outcomes according to the methods of preoperative biliary drainage in periampullary cancers causing obstructive jaundice, and to find out a proper biliary drainage method.
Incidence of Infectious Complications After Biliary Drainage
Change in Total Serum Bilirubin After Drainage
Periampullary Cancers With Obstructive Jaundice
Study Arms / Comparison Groups
Description: biliary drainage : PTBD procedure for obstructive jaundice in patients with periampullary cancer
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Primary Completion Date
Inclusion Criteria: - patient who have periampullary tumors causing obstructive jaundice - patient age: ≥20 and ≤85 - resectable state of disease - no history of previous chemotherapy or radiotherapy - patients without uncontrollable severe cardiovascular, respiratory disease - Karnofsky performance scale ≥70 - informed consent Exclusion Criteria: - patients with distant metastasis or locally advanced disease with major vascular invasion - duodenal cancer - biliary drainage before randomization - previous chemotherapy or radiotherapy - uncontrollable active infection except cholangitis - severe comorbid disease (cardiac, pulmonary, cerebrovascular)
20 Years - 85 Years
Accepts Healthy Volunteers
Korea, Republic of
Korea, Republic of
Seoul National University Hospital