The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy

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Brief Title

The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy

Official Title

The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy

Brief Summary

      The investigators aimed to investigate the effects of salpingectomy and Methotrexate
      administration on ovarian reserve in ectopic pregnancy.
    

Detailed Description

      In this study, the effects of unilateral laparoscopic salpingectomy and single dose of
      systemic Methotrexate administration on ovarian reserve in patients diagnosed with ectopic
      pregnancy were investigated.
    


Study Type

Interventional


Primary Outcome

Ovarian reserve assessment by measuring AMH level.

Secondary Outcome

 Number of participants with treatment related adverse effect on fertility.

Condition

Ectopic Pregnancy

Intervention

Methotrexate

Study Arms / Comparison Groups

 Methotrexate only
Description:  Single dose of systemic Methotrexate administered to 55 patients.

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Drug

Estimated Enrollment

131

Start Date

January 2013

Completion Date

February 2015

Primary Completion Date

February 2015

Eligibility Criteria

        Inclusion Criteria:

          -  ectopic pregnancy diagnosis

        Exclusion Criteria:

          -  history of endometriosis, ovarian surgery, systemic chemotherapy, ART treatment.

          -  patients treated with multiple doses of methotrexate or different surgical procedure
             (salpingostomy, milking)
      

Gender

Female

Ages

18 Years - 45 Years

Accepts Healthy Volunteers

No

Contacts

Ahmet M. Ergenoglu, Ass. Prof., , 

Location Countries

Turkey

Location Countries

Turkey

Administrative Informations


NCT ID

NCT02714998

Organization ID

2013-TIP-043


Responsible Party

Principal Investigator

Study Sponsor

Ege University


Study Sponsor

Ahmet M. Ergenoglu, Ass. Prof., Study Director, Ege University School of Medicine Department of Obstetrics and Gynecology


Verification Date

March 2016