Sensory Symptoms in Tourette Syndrome

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Tourette syndrome
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Brief Title

Sensory Symptoms in Tourette Syndrome

Official Title

Sensory Symptoms in Tourette Syndrome

Brief Summary

      Patients with tics will be asked to complete a series of validated questionnaires (in
      electronic and/or paper format) regarding symptoms and conditions often associated with
      Tourette syndrome, including premonitory urges, sensory experiences, inattention,
      obsessive-compulsive tendencies, anxiety, and depression. Participants will also be asked to
      complete a quality of life assessment. This series of questionnaires will be administered
      annually.

Detailed Description

      Patients with tics will be recruited to participate in an observational study assessing
      extent and variation in non-motor features of Tourette syndrome over time. Each participant
      will complete a battery of validated questionnaires and scales online or in paper format (per
      patient preference), including the Premonitory Urge to Tic Scale (PUTS), the Sensory Gating
      Inventory (SGI), the Sensory Perception Quotient, the World Health Organization ADHD
      Self-Report Screening Scale, and others. These questionnaires will be administered annually
      to patients. For the analysis, participants will be stratified by age into late adolescents
      (18-25 years old) and adults (older than 25 years) since adolescent development ends at
      approximately age 25.

Study Type

Observational

Primary Outcome

Baseline Sensory Perception Quotient score, short form

Secondary Outcome

 Change in Sensory Gating Inventory score at 2 years

Condition

Tourette Syndrome

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Estimated Enrollment

100

Start Date

April 17, 2019

Completion Date

December 2024

Primary Completion Date

March 2024

Eligibility Criteria

        Inclusion Criteria:

          -  diagnosis of Tourette syndrome or other tic disorder

          -  ability to provide informed consent

          -  English fluency

        Exclusion Criteria:

          -  age =< 18 years

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

No

Contacts

David A Isaacs, MD, ,

Location Countries

United States

Location Countries

United States

Administrative Informations

NCT ID

NCT03851484

Organization ID

VUMCSenST

Responsible Party

Principal Investigator

Study Sponsor

Vanderbilt University Medical Center

Study Sponsor

David A Isaacs, MD, Principal Investigator, Vanderbilt University Medical Center

Verification Date

June 2022