Brief Title
Sensory Symptoms in Tourette Syndrome
Official Title
Sensory Symptoms in Tourette Syndrome
Brief Summary
Patients with tics will be asked to complete a series of validated questionnaires (in electronic and/or paper format) regarding symptoms and conditions often associated with Tourette syndrome, including premonitory urges, sensory experiences, inattention, obsessive-compulsive tendencies, anxiety, and depression. Participants will also be asked to complete a quality of life assessment. This series of questionnaires will be administered annually.
Detailed Description
Patients with tics will be recruited to participate in an observational study assessing extent and variation in non-motor features of Tourette syndrome over time. Each participant will complete a battery of validated questionnaires and scales online or in paper format (per patient preference), including the Premonitory Urge to Tic Scale (PUTS), the Sensory Gating Inventory (SGI), the Sensory Perception Quotient, the World Health Organization ADHD Self-Report Screening Scale, and others. These questionnaires will be administered annually to patients. For the analysis, participants will be stratified by age into late adolescents (18-25 years old) and adults (older than 25 years) since adolescent development ends at approximately age 25.
Study Type
Observational
Primary Outcome
Baseline Sensory Perception Quotient score, short form
Secondary Outcome
Change in Sensory Gating Inventory score at 2 years
Condition
Tourette Syndrome
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
100
Start Date
April 17, 2019
Completion Date
December 2024
Primary Completion Date
March 2024
Eligibility Criteria
Inclusion Criteria: - diagnosis of Tourette syndrome or other tic disorder - ability to provide informed consent - English fluency Exclusion Criteria: - age =< 18 years
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
David A Isaacs, MD, ,
Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT03851484
Organization ID
VUMCSenST
Responsible Party
Principal Investigator
Study Sponsor
Vanderbilt University Medical Center
Study Sponsor
David A Isaacs, MD, Principal Investigator, Vanderbilt University Medical Center
Verification Date
June 2022