Brief Title
Training in Hypoxia to Prevent Acute Mountain Sickness
Official Title
Prevention of Acute Mountain Sickness (AMS) by Intermittent Hypoxic Training
Brief Summary
Some studies suggest that high-altitude related illnesses - like acute mountain sickness - could be prevented by acclimatisation, reached at low altitude using training in simulated altitude. The purpose of this study is to determine whether training in hypoxia is suitable to prevent acute mountain sickness.
Detailed Description
In a three week-period, healthy probands undergo 3 times a week a bicycle ergometer training in simulated altitude followed by 1 week passive exposure at simulated low altitude. 5 days after last exposure, a field study starts performing a rapid ascent to the Capanna Regina Margherita (4559m). Acute mountain sickness is assessed by established scoring systems.
Study Type
Interventional
Primary Outcome
Incidence of acute mountain sickness
Secondary Outcome
Severity of acute mountain sickness
Condition
Acute Mountain Sickness
Intervention
hypoxia
Study Arms / Comparison Groups
Hypoxia
Description: training in simulated altitude
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
50
Start Date
June 2008
Completion Date
October 2009
Primary Completion Date
August 2008
Eligibility Criteria
Inclusion Criteria: - healthy - non-smoker - endurance training min. 2x/week Exclusion Criteria: - any diseases - previous exposure to altitudes higher than 2000m (last 6 weeks)
Gender
All
Ages
18 Years - 55 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Kai Schommer, MD, +496221568256, [email protected]
Location Countries
Germany
Location Countries
Germany
Administrative Informations
NCT ID
NCT00886912
Organization ID
S-160/2008
Study Sponsor
Heidelberg University
Study Sponsor
Kai Schommer, MD, Principal Investigator, Departement of Sports Medicine, University of Heidelberg
Verification Date
April 2009