Training in Hypoxia to Prevent Acute Mountain Sickness

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Acute mountain sickness
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Brief Title

Training in Hypoxia to Prevent Acute Mountain Sickness

Official Title

Prevention of Acute Mountain Sickness (AMS) by Intermittent Hypoxic Training

Brief Summary

      Some studies suggest that high-altitude related illnesses - like acute mountain sickness -
      could be prevented by acclimatisation, reached at low altitude using training in simulated
      altitude. The purpose of this study is to determine whether training in hypoxia is suitable
      to prevent acute mountain sickness.

Detailed Description

      In a three week-period, healthy probands undergo 3 times a week a bicycle ergometer training
      in simulated altitude followed by 1 week passive exposure at simulated low altitude. 5 days
      after last exposure, a field study starts performing a rapid ascent to the Capanna Regina
      Margherita (4559m). Acute mountain sickness is assessed by established scoring systems.

Study Type

Interventional

Primary Outcome

Incidence of acute mountain sickness

Secondary Outcome

 Severity of acute mountain sickness

Condition

Acute Mountain Sickness

Intervention

hypoxia

Study Arms / Comparison Groups

 Hypoxia
Description:  training in simulated altitude

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Other

Estimated Enrollment

50

Start Date

June 2008

Completion Date

October 2009

Primary Completion Date

August 2008

Eligibility Criteria

        Inclusion Criteria:

          -  healthy

          -  non-smoker

          -  endurance training min. 2x/week

        Exclusion Criteria:

          -  any diseases

          -  previous exposure to altitudes higher than 2000m (last 6 weeks)

Gender

All

Ages

18 Years - 55 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Kai Schommer, MD, +496221568256, [email protected]

Location Countries

Germany

Location Countries

Germany

Administrative Informations

NCT ID

NCT00886912

Organization ID

S-160/2008

Study Sponsor

Heidelberg University

Study Sponsor

Kai Schommer, MD, Principal Investigator, Departement of Sports Medicine, University of Heidelberg

Verification Date

April 2009