Acclimatization Mechanisms During Ascent to 7500m

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Brief Title

Acclimatization Mechanisms During Ascent to 7500m

Official Title

Acclimatization Mechanisms During Ascent to 7500m. Effects of Ascent Protocol on Acute Mountain Sickness and Cardiorespiratory Physiology

Brief Summary

      The trial evaluates the role of ascent protocol on acute mountain sickness and
      cardio-respiratory physiology during an ascent to Muztagh Ata (7546m). Two groups of
      mountaineers ascend with different acclimatization time to the summit. The prevalence and
      severity of symptoms of acute mountain sickness are evaluated along with physiologic
      variables.
    



Study Type

Interventional


Primary Outcome

acute mountain sickness

Secondary Outcome

 mountaineering success, oxygen saturation, breathing pattern

Condition

Acute Mountain Sickness

Intervention

ascent protocol

Study Arms / Comparison Groups

 1
Description:  fast ascent

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Behavioral

Estimated Enrollment

37

Start Date

March 2005

Completion Date

December 2005

Primary Completion Date

December 2005

Eligibility Criteria

        Inclusion Criteria:

          -  Healthy, physically fit subject

          -  Mountaineering experience

        Exclusion Criteria:

          -  Any type of cardiac or respiratory disease

          -  Regular intake of any medication

          -  History of high altitude pulmonary oedema

          -  Severe acute mountain sickness at altitudes below 3500m or high altitude cerebral
             oedema.
      

Gender

All

Ages

18 Years - 70 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Konrad E Bloch, MD, , 



Administrative Informations


NCT ID

NCT00603122

Organization ID

EK-1189

Secondary IDs

SNSF 3200B0-108300


Study Sponsor

University of Zurich

Collaborators

 Swiss National Science Foundation

Study Sponsor

Konrad E Bloch, MD, Principal Investigator, Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland


Verification Date

May 2014