Brief Title
Prevention of Acute Mountain Sickness by Intermittent Hypoxia
Official Title
Prevention of Acute Mountain Sickness by Sleeping at Simulated Altitude (Normobaric Hypoxia)
Brief Summary
Acclimatization by mountaineering prior to high altitude sojourns have shown to be effective in prevention of acute mountain sickness (AMS). The aim of this study is to investigate whether intermittent exposure to normobaric hypoxia during sleep is also effective to prevent AMS.
Study Type
Interventional
Primary Outcome
incidence of acute mountain sickness
Secondary Outcome
Sleep quality
Condition
Acute Mountain Sickness
Intervention
Hypoxic Exposure
Study Arms / Comparison Groups
Normoxia
Description: Sleeping in normoxia for 14 nights prior to one night at 4500 m
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
75
Start Date
March 2006
Completion Date
July 2007
Eligibility Criteria
Inclusion Criteria: - healthy Exclusion Criteria: - Altitude exposure above 2000 m 8 weeks prior or during the study
Gender
Male
Ages
18 Years - 50 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Christoph Dehnert, MD, ,
Location Countries
Germany
Location Countries
Germany
Administrative Informations
NCT ID
NCT00559832
Organization ID
039/2006
Study Sponsor
Heidelberg University
Study Sponsor
Christoph Dehnert, MD, Principal Investigator, University Hospital Heidelberg
Verification Date
November 2007