Physiological Adaptations to Simulated Intermittent Altitude on Human Health and Performance

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Brief Title

Physiological Adaptations to Simulated Intermittent Altitude on Human Health and Performance

Official Title

Investigation of Physiological Adaptations to Simulated Intermittent Altitude on Human Health and Performance

Brief Summary

      The investigators expect to find that different intensity and altitude exposure levels will
      show what kind of intermittent exposure protocol is more beneficial to athletes and healthy
      individuals that experience acute exposure to altitude during exercise. This may furthermore
      be related to acute altitude exposure for recreational exercise use as well.
    



Study Type

Interventional


Primary Outcome

Change in hemoglobin

Secondary Outcome

 Change in peak VO2

Condition

Altitude Hypoxia

Intervention

Simulated altitude

Study Arms / Comparison Groups

 Effect of heart rate training in simulated altitude
Description:  Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining >65% max heart rate during room air based maximal peak work.

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

72

Start Date

January 1, 2019

Completion Date

March 2021

Primary Completion Date

December 2020

Eligibility Criteria

        Inclusion criteria:

          -  18-70 years of age,

          -  history of good health,

          -  generally active to competitive athletes.

        Exclusion criteria:

          -  History of cardiac or pulmonary disease,

          -  not currently active,

          -  unable to exercise or meet study requirements (e.g., number of sessions),

          -  live at altitude (>2,100m or 7,000ft).
      

Gender

All

Ages

18 Years - 70 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Courtney M Wheatley, , 

Location Countries

United States

Location Countries

United States

Administrative Informations


NCT ID

NCT03743610

Organization ID

18-000484


Responsible Party

Principal Investigator

Study Sponsor

Mayo Clinic


Study Sponsor

Courtney M Wheatley, Principal Investigator, Mayo Clinic


Verification Date

October 2019