The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

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Brief Title

The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Official Title

The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Brief Summary

      To find the safe effective lowest light dose for photodynamic therapy (PDT). in the treatment
      of central serous chorioretinopathy.
    



Study Type

Interventional


Primary Outcome

Changes of best corrected visual acuity

Secondary Outcome

 Change of central retinal thickness, success rate, recurrence rate, and complications

Condition

Central Serous Chorioretinopathy

Intervention

Photodynamic therapy

Study Arms / Comparison Groups

 50% group
Description:  power of PDT is applied to the patients at 50% of the full energy based on TAP study.

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Procedure

Estimated Enrollment

45

Start Date

June 2012

Completion Date

March 2015

Primary Completion Date

October 2014

Eligibility Criteria

        Inclusion Criteria:

          1. Idiopathic detachment of the neurosensory retina with a focal leak at the level of the
             RPE with FA

          2. Presence of SRF and/or serous pigment epithelial detachment on optical coherence
             tomography (OCT)

          3. Presence of abnormal dilated choroidal vasculature in ICGA

          4. Patients with symptomatic CSC of at least 3 months duration

        Exclusion Criteria:

          1. Patients who received any previous treatment, including PDT or focal thermal laser
             photocoagulation for CSC, or who had evidence of CNV, PCV, or other maculopathy on
             clinical examination, FA, or ICGA

          2. Patients receiving exogenous corticosteroid treatment

          3. Patients with systemic diseases such as Cushing's disease or renal diseases

          4. Pregnant patients
      

Gender

All

Ages

20 Years - 70 Years

Accepts Healthy Volunteers

No

Contacts

, 82-53-620-4191, [email protected]

Location Countries

Korea, Republic of

Location Countries

Korea, Republic of

Administrative Informations


NCT ID

NCT01630863

Organization ID

YUH-12-007-D4


Responsible Party

Principal Investigator

Study Sponsor

Yeungnam University College of Medicine


Study Sponsor

, , 


Verification Date

February 2015