Brief Title
Effect of Helicobacter Pylori Treatment on Idiopathic Central Serous Chorioretinopathy (ICSCR)
Official Title
Effect of Helicobacter Pylori Treatment on Remission of Idiopathic Central Serous Chorioretinopathy (ICSCR)
Brief Summary
Etiology of ICSCR is not known however recent studies regard the role of immunologic and
infectious processes in the pathogenesis of ICSCR.one of these hypothesis is the role of
helicobacter pylori in the pathogenesis of ICSCR so perhaps treatment of h pylori have
positive effect on the remission of ICSCR.
Detailed Description
we will choose 50 cases of patients with ICSCR who are infected with h.pylori.25 cases will
receive anti h.pylori regiment and 25 cases as controls will receive no medication.then we
will compare the time of submacular fluid resorption and macular thickness and visual acuity
among these two groups.
Study Phase
Phase 1/Phase 2
Study Type
Interventional
Primary Outcome
Subretinal fluid level
Secondary Outcome
time of sub macular fluid absorption
Condition
Central Serous Chorioretinopathy
Intervention
omeprazole, Amoxicillin, metronidazole
Study Arms / Comparison Groups
1
Description: Oral Amoxicillin Capsule Metronidazole Tablet Omeprazole Capsule
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Drug
Estimated Enrollment
50
Start Date
March 2008
Completion Date
January 2009
Primary Completion Date
October 2008
Eligibility Criteria
Inclusion Criteria:
- the persons who are infected with helicobacter pylori and have ICSCR
Exclusion Criteria:
- history of previous eye surgery ,to have indication of laser therapy,corticosteroid
therapy,pregnancy,
Gender
All
Ages
28 Years - 40 Years
Accepts Healthy Volunteers
No
Contacts
Alireza Javadzadeh, ,
Location Countries
Iran, Islamic Republic of
Location Countries
Iran, Islamic Republic of
Administrative Informations
NCT ID
NCT00817245
Organization ID
86-47
Study Sponsor
Tabriz University
Study Sponsor
Alireza Javadzadeh, Study Chair, Alireza Javadzadeh
Verification Date
January 2009