Study of Photodynamic Therapy (PDT) in Patients With Central Serous Chorioretinopathy (CSC)

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Brief Title

Study of Photodynamic Therapy (PDT) in Patients With Central Serous Chorioretinopathy (CSC)

Official Title

A Randomized, Double-masked, Multicenter, Controlled Study of Photodynamic Therapy in Patients With Central Serous Chorioretinopathy

Brief Summary

      The purpose of this study is to determine the safety and efficacy of PDT at 30% verteporfin
      dose in the treatment of CSC.
    


Study Phase

Phase 4

Study Type

Interventional


Primary Outcome

Change from baseline in BCVA

Secondary Outcome

 Leakage at RPE level in FA

Condition

Central Serous Chorioretinopathy

Intervention

PDT

Study Arms / Comparison Groups

 50% dose PDT
Description:  patients in this group was given 50% verteporfin dose PDT

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Procedure

Estimated Enrollment

131

Start Date

December 2010

Completion Date

December 2014

Primary Completion Date

December 2012

Eligibility Criteria

        Inclusion Criteria:

          -  patients with CSC

          -  patients signed the ICF

          -  patients with course of CSC less than 6 months

          -  patients did not undertake any treatment for CSC

        Exclusion Criteria:

          -  patients with porphyria

          -  patients allergic to verteporfin

          -  pregnant or nursing women

          -  poor patients compliance

          -  sever liver dysfunction

          -  dioptric media opacities which make it difficult to exam fundus
      

Gender

All

Ages

18 Years - 50 Years

Accepts Healthy Volunteers

No

Contacts

Mingwei Zhao, M.D, , 

Location Countries

China

Location Countries

China

Administrative Informations


NCT ID

NCT01574430

Organization ID

PDTCSC-CHINA


Responsible Party

Principal Investigator

Study Sponsor

Peking University People's Hospital


Study Sponsor

Mingwei Zhao, M.D, Study Director, Peking University People's Hospital


Verification Date

August 2016