Brief Title
Protection Against Benzene Toxicity
Official Title
NQO1 in Protection Against Benzene Toxicity
Brief Summary
We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.
Study Type
Observational
Condition
Leukemia
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Start Date
July 1998
Completion Date
June 2001
Eligibility Criteria
Healthy adult volunteers with blood counts in normal ranges and without evidence of hepatitis or HIV infection.
Gender
All
Ages
21 Years - 65 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
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Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT00011453
Organization ID
9554-CP-001
Study Sponsor
National Institute of Environmental Health Sciences (NIEHS)
Study Sponsor
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Verification Date
July 2002