Brief Title
Blood Transplantation for Patients With Hematologic Malignancies or Bone Marrow Failure States
Official Title
Megadose T-cell Depleted HLA-nonidentical Blood Progenitor Cell Transplantation for Patients With Hematologic Malignancies or Bone Marrow Failure States
Brief Summary
The purpose of this study is to assess early treatment failure within 100 days and to assess the effect of this regimen on engraftment, GVHD, immune recovery, relapse of malignancy and survival.
Study Type
Interventional
Condition
Leukemia
Intervention
Megadose T-cell Depleted HLA-nonidentical Blood Progenitor Cell Transplantation
Study Arms / Comparison Groups
Megadose T cell depleted
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Procedure
Estimated Enrollment
7
Start Date
August 14, 1996
Completion Date
September 20, 2004
Primary Completion Date
September 20, 2004
Eligibility Criteria
- Patients with acute leukemia, lymphoma that failed to respond or relapsed after chemotherapy or CML beyond first chronic phase. - Patients with aplastic anemia or myelodysplasia which failed to respond to primary therapy are eligible. - Patients with low grade lymphoma or CLL will only be eligible if they failed two chemotherapy regimens and have stage IV disease. - Patients must be
Gender
All
Ages
N/A - 49 Years
Accepts Healthy Volunteers
No
Contacts
, ,
Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT00038779
Organization ID
DM96-122
Responsible Party
Sponsor
Study Sponsor
M.D. Anderson Cancer Center
Study Sponsor
, ,
Verification Date
October 2018