Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia

Brief Title

Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia

Official Title

Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia Based on EDC Data Management Platform

Brief Summary

      To ascertain the risk factors of AA in ZheJiang Province of China at the moment, especially
      the comprehensive multiple factors risks. The author conducted a case-control research
      included 338 AA cases and 1464 controls. Subjects were surveyed using same standard
      questionnaire including personal data, past histories of diseases, family history and
      histories of occupational and daily exposure to harmful substances. Single and multiple
      Logistic regression analyses were made using SPSS17.0 on the dates to study potential factors
      in the development of AA.
    

Study Type

Observational

Primary Outcome

the items about daily Exposures

Secondary Outcome

 Individual Behaviours

Condition

Aplastic Anemia

Intervention

AA or not

Study Arms / Comparison Groups

 AA Group

Description:  All the patients of AA group met a AA diagnostic criteria；

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Status

Other

Estimated Enrollment

1802

Start Date

January 1, 2003

Completion Date

January 1, 2014

Primary Completion Date

January 1, 2014

Eligibility Criteria

        Inclusion Criteria:

          -  All the patients of AA group met a AA diagnostic criteria；The control group were
             chosen from other departments who were under acute infection (such as pneumonia),
             acute abdominal emergency (such as appendicitis), cataract surgery;

          -  1-65 years old, male or female;

          -  Sign the informed consent.

        Exclusion Criteria:

          -  With myelodysplastic syndrome, leukaemia, multiple myeloma,megaloblastic anaemia,
             paroxysmal sleep hemoglobinuria disease blood disease, etc.

          -  History of tumor, radiation or chemotherapy, once accept the immunological therapy,
             autoimmune diseases or allergic disease patients;

          -  Patients with neurological diseases.
      

Gender

All

Ages

1 Year - 65 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

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NCT ID

NCT03208647

Organization ID

MCS-EDC-1802

Responsible Party

Sponsor-Investigator

Study Sponsor

Shengyun Lin

Study Sponsor

, , 

Verification Date

July 2017