Brief Title
Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia
Official Title
Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia Based on EDC Data Management Platform
Brief Summary
To ascertain the risk factors of AA in ZheJiang Province of China at the moment, especially the comprehensive multiple factors risks. The author conducted a case-control research included 338 AA cases and 1464 controls. Subjects were surveyed using same standard questionnaire including personal data, past histories of diseases, family history and histories of occupational and daily exposure to harmful substances. Single and multiple Logistic regression analyses were made using SPSS17.0 on the dates to study potential factors in the development of AA.
Study Type
Observational
Primary Outcome
the items about daily Exposures
Secondary Outcome
Individual Behaviours
Condition
Aplastic Anemia
Intervention
AA or not
Study Arms / Comparison Groups
AA Group
Description: All the patients of AA group met a AA diagnostic criteria;
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
1802
Start Date
January 1, 2003
Completion Date
January 1, 2014
Primary Completion Date
January 1, 2014
Eligibility Criteria
Inclusion Criteria: - All the patients of AA group met a AA diagnostic criteria;The control group were chosen from other departments who were under acute infection (such as pneumonia), acute abdominal emergency (such as appendicitis), cataract surgery; - 1-65 years old, male or female; - Sign the informed consent. Exclusion Criteria: - With myelodysplastic syndrome, leukaemia, multiple myeloma,megaloblastic anaemia, paroxysmal sleep hemoglobinuria disease blood disease, etc. - History of tumor, radiation or chemotherapy, once accept the immunological therapy, autoimmune diseases or allergic disease patients; - Patients with neurological diseases.
Gender
All
Ages
1 Year - 65 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
, ,
Administrative Informations
NCT ID
NCT03208647
Organization ID
MCS-EDC-1802
Responsible Party
Sponsor-Investigator
Study Sponsor
Shengyun Lin
Study Sponsor
, ,
Verification Date
July 2017