Brief Title
Acromegaly - Before and After Treatment
Official Title
Sleep Apnea, Circulation and Metabolism in Acromegaly - Before and After Treatment
Brief Summary
The aim of the study is to investigate sleep apnea, circulation and metabolism in acromegaly before and after surgery and/or medical treatment.
Detailed Description
Acromegaly is a rare disease caused by a growth hormone (GH) producing pituitary adenoma. Surgery is primary treatment, whereas medical treatment with a somatostatin analogue (SA), which suppresses GH secretion and reduces tumour size, is used when surgery is insufficient or unfeasible. Acromegaly is associated with metabolic abnormalities which contributes to an increased morbidity and mortality if left untreated. To which extend these abnormalities reverses after treatment, and if treatment modality influences the outcome, remain elusive. The aim of the study is to investigate sleep apnea, circulation and metabolism in acromegaly before and after surgery and/or medical treatment
Study Type
Observational
Primary Outcome
Sleep apnea
Secondary Outcome
Heartfunction
Condition
Acromegaly
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
20
Start Date
October 1, 2017
Completion Date
December 1, 2022
Primary Completion Date
December 1, 2022
Eligibility Criteria
Inclusion Criteria: - Recently diagnosed with acromegaly - Age above 18 - Written consent Exclusion Criteria: - Pregnancy
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
No
Contacts
Jens Otto L Jørgensen, Porfessor, +45 23837420, [email protected]
Location Countries
Denmark
Location Countries
Denmark
Administrative Informations
NCT ID
NCT03431727
Organization ID
1-10-72-126-16
Responsible Party
Sponsor
Study Sponsor
University of Aarhus
Study Sponsor
Jens Otto L Jørgensen, Porfessor, Principal Investigator, Aarhus University Hospital, Department of internal medicine and endocrinology
Verification Date
December 2020