The Use of Shear Wave Elastography, Transvaginal Ultrasound and Pelvic MRI in the Diagnosis of Adenomyosis

Learn more about:
Related Clinical Trial
The Use of Shear Wave Elastography, Transvaginal Ultrasound and Pelvic MRI in the Diagnosis of Adenomyosis Long-term Use of Mifepristone in the Treatment of Adenomyosis Radiofrequency Ablation of Adenomyosis Determination of the Incidence of Endometriosis and or Adenomyosis in Patients Diagnosed With Polycystic Ovary Syndrome, or the Incidence of Polycystic Ovary Syndrome in Patients Diagnosed With Endometriosis and or Adenomyosis The Effect of Adenomoyosis on Pregnancy Outcomes Observational Study of Patients Suffering From Endometriosis and Adenomyosis Factors Associated With Adenomyosis and a Clinical Scoring System for the Diagnosis Quality of Life After Hysterectomy (AdenoQOL) Low Molecular Weight Heparin on the Adenomyosis Patients’IVF-ET Outcome Diagnosis of Adenomyosis Using Ultrasound, Elastography and MRI Clinical and Molecular Study of Endometriosis and Adenomyosis Surgical Success After Laparoscopic vs Abdominal Hysterectomy Electronic Catheter Stethoscope Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy Does 3D Laparoscopy Improve Vaginal Cuff Suture Time? Single-port Access Laparoscopic-assisted Vaginal Hysterectomy Uterine Artery Embolization for Symptomatic Fibroids Oxytocin in MRI-HIFU To Compare to 2-channel and Multiple-channel Single Port Laparoscopic-assisted Vaginal Hysterectomy Effect of Addition of Steroids on Duration of Analgesia Paracervical Block in Laparoscopic Hysterectomy Use of Dexamethasone in Uterine Artery Embolization Treatment of Benign Uterine Disorders Using High Intensity Focused Ultrasound (MR-HIFU) Comparison of Estrogen-progestin Therapy in Continuous Regimen Versus Combination Estrogen-progestin Therapy in Continuous Regimen Plus Levonorgestrel-releasing Intrauterine System (LNG-IUS) Dienogest for Treatment of Adenomyotic Uteri Health-Related QoL Among Women Receiving Hysterectomy in NTUH Development and Validation of EHP-30 (Hong Kong Chinese Version) for Patients With Endometriosis and Adenomyosis Adenomyosis and Ulipristal Acetate Efficacy of Acupuncture on Chronic Pelvic Pain in Women With Endometriosis or Adenomyosis LNG-IUS for Treatment of Dysmenorrhea Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis Adenomyosis: Genomic Mechanisms and Biological Response What Are we Missing? Diagnosing Uterine Adenomyosis Using Ultrasound Elastography Comparing Efficacy of Microwave vs Embolization Treatment for Adenomyosis Role of Dienogest in the Treatment of Patient With Symptomatic Adenomyosis Comparison of the Operation and Medical Treatment of Endometriosis and Adenomyosis A Prospective Study of Diagnostic Accuracy of Ultrasound Placebo-controlled Proof of Concept Study of Epelsiban in Women With Adenomyosis A Multi-omics Study of Adenomyosis Norwegian Adenomyosis Study II: Gene Expression Profiling of Adenomyosis Levonorgestrel Intrauterine System and Adenomyosis Validation of the Adenomyosis Calculator Levonorgestrel-releasing Intrauterine System Versus a Low-dose Combined Oral Contraceptive for Management of Adenomyosis Uteri Modified Downregulation for Women With Adenomyosis of the Uterus Prior to Frozen-thawed Embryo Transfer. New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms High-intensity Focused Ultrasound in Treatment of Uterine Adenomyosis Evaluation of Therapeutic Effect and Safety of Mifepristone in the Treatment of Adenomyosis Norwegian Adenomyosis Study III: Peristalsis Histopathological Diagnosis of Adenomyosis Norwegian Adenomyosis Study I Vaginal Bromocriptine for Treatment of Adenomyosis Levonorgestrel-releasing Intrauterine System for the Treatment of Symptomatic Adenomyosis

Brief Title

The Use of Shear Wave Elastography, Transvaginal Ultrasound and Pelvic MRI in the Diagnosis of Adenomyosis

Official Title

The Use of Shear Wave Elastography, Transvaginal Ultrasound and Pelvic MRI in the Diagnosis of Adenomyosis

Brief Summary

      In this prospective cohort study, the patients who were diagnosed with either uterine fibroid
      (control group) or adenomyosis (study group), were examined with transvaginal ultrasound and
      shear wave elastography. Definitive diagnosis was established by pelvic MRI. Shear wave
      elastography data of both groups were compared. Features of adenomyosis on transvaginal
      ultrasound were also recorded for study group.
    

Detailed Description

      In this prospective cohort study, the patients who applied to the Gynecology and Infertility
      Outpatient Clinic in Istanbul University Faculty of Medicine between October 2018 and October
      2021 due to abnormal uterine bleeding, pelvic pain, infertility were evaluated. The patients
      who were diagnosed with adenomyosis and uterine myoma according to clinical evaluation were
      included and grouped. Clinical diagnosis were confirmed with contrast enhanced pelvic
      magnetic resonance imaging. No histopathological confirmation were included in this study. 34
      patients were included in adenomyosis group and 31 patients were included in myoma group. All
      patients were evaluated with shear wave elastography; 3 regions of interest were selected for
      each elastographic evaluation. Average shear values were determined automatically; then,
      minimum and maximum mean shear values were recorded accordingly. Elastography values of both
      groups were compared in order to detect any statistically significant difference between 2
      groups. In addition to elastography evaluation, the compatibility of transvaginal ultrasound
      and magnetic resonance were evaluated.
    


Study Type

Interventional


Primary Outcome

Elastography data of adenomyotic lesions and fibroids

Secondary Outcome

 Ultrasonographic features of adenomyotic lesions

Condition

Adenomyosis

Intervention

Shear wave elastography

Study Arms / Comparison Groups

 Adenomyosis
Description:  Patients who were diagnosed with adenomyosis according to pelvic MRI were examined with transvaginal ultrasound. Certain ultrasonographic features of adenomyosis ( asymmetrical uterine wall thickening, myometrial cysts, fan shaped lines and shadows, presence of irregular junctional zone, presence of clue sign, global enlargement) were recorded. Then the patients were examined with shear wave elastography. Maximum and minimum median shear wave values were recorded through the selected regions of interest.

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Device

Estimated Enrollment

65

Start Date

October 1, 2018

Completion Date

January 1, 2022

Primary Completion Date

October 1, 2021

Eligibility Criteria

        Inclusion Criteria:

          -  Patients who applied to outpatient clinic due to abnormal uterine bleeding, pelvic
             pain, infertility.

        Exclusion Criteria:

          -  Patients who are currently pregnant or has current malignancy, use combined oral
             contraceptives, gonadotropin releasing hormone agonist, intrauterine device or
             currently taking hormonal replacement therapy.
      

Gender

Female

Ages

18 Years - 60 Years

Accepts Healthy Volunteers

No

Contacts

, , 

Location Countries

Turkey

Location Countries

Turkey

Administrative Informations


NCT ID

NCT05419414

Organization ID

2018/1080


Responsible Party

Principal Investigator

Study Sponsor

Istanbul University


Study Sponsor

, , 


Verification Date

June 2022