The Effect of Adenomoyosis on Pregnancy Outcomes

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Brief Title

The Effect of Adenomoyosis on Pregnancy Outcomes

Official Title

Adverse Obstetrical Outcomes for Women With Adenomyosis

Brief Summary

      Adenomyosis can be defined as the settling of endometrial gland cells in the myometrium and
      deformity in the uterus and the prevalence of adenomyosis is according to the patient
      population and countries around 20%. There are recent publications reporting that this rate
      increases up to 50% in women dealing with infertility. In adenomyosis, where uterine
      morphology is affected, it is not thought that the uterus, which is expected to provide many
      morphological adaptations during pregnancy, will not be affected. Therefore, in this
      prospective study, it was planned to investigate the effects of adenomyosis during pregnancy.

      For this study the presence of adenomyosis will be questioned by using ultrasonographic
      morphological uterine limitation (MUSA) in women who apply to the outpatient clinic with
      suspicion of pregnancy and undergo transvaginal ultrasonography for the diagnosis of
      pregnancy before sixth gestational week.

      Patients will be divided into two groups according to the presence of adenomyosis and
      pregnancy complications such as preterm labor, premature rupture of membranes, cesarean
      section rates, preeclampsia, fetal malpresentation and preeclampsia will be compared between
      the groups.
    



Study Type

Observational [Patient Registry]


Primary Outcome

Pregnancy complication

Secondary Outcome

 Pregnancy complication

Condition

Adenomyosis

Intervention

Non intervention

Study Arms / Comparison Groups

 Adenomyosis Group
Description:  

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

150

Start Date

May 20, 2021

Completion Date

December 2022

Primary Completion Date

August 2022

Eligibility Criteria

        Inclusion Criteria:

          -  Age between 18-35 years

          -  Being diagnosed before the 6th gestational week

          -  Having all pregnancy follow-ups and deliveries in our hospital

        Exclusion Criteria:

          -  Previous uterine surgery

          -  Multiple pregnancies

          -  Pregnant women with uterine malformations

          -  Pregnant women with fetal anomalies

          -  Those who got pregnant using assisted reproductive technique
      

Gender

Female

Ages

18 Years - 35 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Ahkam Göksel Kanmaz, Assoc. Prof., (0232) 373 89 21, [email protected]

Location Countries

Turkey

Location Countries

Turkey

Administrative Informations


NCT ID

NCT04894292

Organization ID

TepecikTRH-001


Responsible Party

Principal Investigator

Study Sponsor

Tepecik Training and Research Hospital


Study Sponsor

Ahkam Göksel Kanmaz, Assoc. Prof., Study Director, Tepecik Education and Research Hospital


Verification Date

May 2021