Brief Title
The Effect of Adenomoyosis on Pregnancy Outcomes
Official Title
Adverse Obstetrical Outcomes for Women With Adenomyosis
Brief Summary
Adenomyosis can be defined as the settling of endometrial gland cells in the myometrium and deformity in the uterus and the prevalence of adenomyosis is according to the patient population and countries around 20%. There are recent publications reporting that this rate increases up to 50% in women dealing with infertility. In adenomyosis, where uterine morphology is affected, it is not thought that the uterus, which is expected to provide many morphological adaptations during pregnancy, will not be affected. Therefore, in this prospective study, it was planned to investigate the effects of adenomyosis during pregnancy. For this study the presence of adenomyosis will be questioned by using ultrasonographic morphological uterine limitation (MUSA) in women who apply to the outpatient clinic with suspicion of pregnancy and undergo transvaginal ultrasonography for the diagnosis of pregnancy before sixth gestational week. Patients will be divided into two groups according to the presence of adenomyosis and pregnancy complications such as preterm labor, premature rupture of membranes, cesarean section rates, preeclampsia, fetal malpresentation and preeclampsia will be compared between the groups.
Study Type
Observational [Patient Registry]
Primary Outcome
Pregnancy complication
Secondary Outcome
Pregnancy complication
Condition
Adenomyosis
Intervention
Non intervention
Study Arms / Comparison Groups
Adenomyosis Group
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Other
Estimated Enrollment
150
Start Date
May 20, 2021
Completion Date
December 2022
Primary Completion Date
August 2022
Eligibility Criteria
Inclusion Criteria: - Age between 18-35 years - Being diagnosed before the 6th gestational week - Having all pregnancy follow-ups and deliveries in our hospital Exclusion Criteria: - Previous uterine surgery - Multiple pregnancies - Pregnant women with uterine malformations - Pregnant women with fetal anomalies - Those who got pregnant using assisted reproductive technique
Gender
Female
Ages
18 Years - 35 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Ahkam Göksel Kanmaz, Assoc. Prof., (0232) 373 89 21, [email protected]
Location Countries
Turkey
Location Countries
Turkey
Administrative Informations
NCT ID
NCT04894292
Organization ID
TepecikTRH-001
Responsible Party
Principal Investigator
Study Sponsor
Tepecik Training and Research Hospital
Study Sponsor
Ahkam Göksel Kanmaz, Assoc. Prof., Study Director, Tepecik Education and Research Hospital
Verification Date
May 2021