The Link Between Periodontitis, Smoking and Oral Cancer
Analysis of the Link Between Periodontitis, Smoking and Oral Cancer: Cohort Study
Periodontitis is a widely prevalent disease worldwide that has serious public health consequences. Its prognosis includes tooth loss and edentulism, a condition that negatively affects chewing causing functional disability; and esthetics causing social impairment. Consequently, periodontitis may end up causing marked impairment of the quality of life of the affected patients, impairment of general health and increasing the dental care costs significantly. Changes in the oral mucosa arise by primary products resulting from tissue breakdown due to gingivitis. It then triggers the host cells to produce proteinases that mediate loss of marginal periodontal ligaments, apical migration of the junctional epithelium and apical spread of bacterial biofilm. Therefore, this research aims to identify the risk of smoking to both periodontitis and oral cancer, and the risk of periodontitis to oral cancer.
biopsy for oral cancer
Study Arms / Comparison Groups
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
August 12, 2021
January 30, 2032
Primary Completion Date
October 12, 2031
Inclusion Criteria: - Patients 18 years or older. Exclusion Criteria: - Patients with any systemic diseases. - Pregnant females. - Handicapped and mentally retarded patients. - Patients undergoing radiotherapy. - Patients having oral cancer
18 Years - N/A
Accepts Healthy Volunteers
, 01001874257, [email protected]