Brief Title
Systematic Pelvic Lymphadenectomy Versus no Lymphadenectomy in Clinical Stage I-II Endometrial Cancer
Brief Summary
The purpose of this trial is to determine whether the addition of systematic pelvic lymphadenectomy to hysterectomy with bilateral adnexectomy improves disease-free survival (DFS) and overall survival (OS) in patients with preoperatively supposed Stage I-II endometrial cancer
Study Type
Interventional
Condition
Endometrial Cancer
Intervention
Systematic pelvic lymphadenectomy
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Procedure
Eligibility Criteria
Inclusion Criteria: - Histologically proven endometrioid or adenosquamous endometrial carcinoma. - Patients having myometrial invasion - Age =/< 75 years - Informed consent. Exclusion Criteria: - Serous papillary and clear cell tumors. - Karnofsky index < 80 or severe diseases contraindicating surgery - Concomitant neoplasia (basalioma cutis excluded) - Distant metastasis or abdominal metastasis detected intraoperatively. - Absence of myometrial invasion at frozen section.
Gender
Female
Ages
N/A - 75 Years
Accepts Healthy Volunteers
No
Contacts
Pierluigi Benedetti Panici, Full Professor, ,
Administrative Informations
NCT ID
NCT00482300
Organization ID
PTC-CBM-15
Study Sponsor
University of Roma La Sapienza
Study Sponsor
Pierluigi Benedetti Panici, Full Professor, Study Chair, Department of Obstetrics and Gynecology University La Sapienza of Rome
Verification Date
March 2007