Brief Title
Retrospective Study to Evaluate the Feasibility of Ovarian Preservation in Patients With Endometrial Carcinoma
Official Title
Study for Elevate the Feasibility of Ovarian Preservation With Endometrial Carcinoma
Brief Summary
Endometrial cancer is one of the most common female malignancies in the United States, and
has increased in incidence in Taiwan in recent decades.A recent population-based analysis
noted that 4% of endometrial cancers occurred in women aged 40 years or younger, furthermore
it is up to 15% in Taiwan according to the data of cancer registry. The standard treatment of
endometrial cancer results in surgical menopause and places patients at risk for the
long-term sequelae of estrogen deprivation. The goal of this study was to determine the
frequency of a coexisting ovarian malignancy and to evaluate the outcome of ovarian
preservation in women with treatment for endometrial cancer.
Detailed Description
we reviewed the cases with early stage of endometrial cancer who have primary staging surgery
between January 1989 to December 2009. The enrolled patients will be divided into two group
(oophorectomy vs. ovary preservation) for analysis:the outcome and recurrence type.To
evaluate the outcome of ovarian preservation in women with endometrial cancer .
Study Type
Observational
Primary Outcome
from the time of diagnosis to the time of disease recurrence or last follow time
Condition
Endometrial Cancer
Intervention
surgery
Study Arms / Comparison Groups
ovarian preservation
Description: endometrial cancer with ovarian preservation
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Procedure
Estimated Enrollment
300
Start Date
August 2000
Completion Date
December 2012
Primary Completion Date
December 2011
Eligibility Criteria
Inclusion Criteria:
- early stage endometrial cancer after primary surgery exclusion criteria:
- MMMT, type 2 endometrial cancer
Gender
Female
Ages
25 Years - 70 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Yi-Jen Chen, 886-2-28757566, [email protected]
Location Countries
Taiwan
Location Countries
Taiwan
Administrative Informations
NCT ID
NCT01560026
Organization ID
VHG0500
Responsible Party
Principal Investigator
Study Sponsor
Taipei Veterans General Hospital, Taiwan
Study Sponsor
Yi-Jen Chen, Study Chair, Department of Obstetric and Gynecology, Taipei Veterans General Hospital
Verification Date
March 2012