Meir Medical Center – Endometrial Cancer

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Recently the general medical literature has become aware that the use of certain long-acting
insulin analogues could potentially increase cancer risk.During the last few years the
investigators group generated information of both scientific and clinical relevance on the
proliferative and anti-apoptotic actions of insulin analogues. The goal of this project is
to evaluate the hypothesis that the proliferative and signalling activities elicited by
insulin analogues may have a impact on tumor behavior. In this study the investigators will
asses the biological actions of insulin analogs in primary tumor cells of endometrial and
colon cancer.

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