Brief Title
Prospective Radiological Study of HRCT to Predict Pathological Noninvasiveness in NSCLC
Official Title
Prospective Radiological Study of HRCT to Predict Pathological Noninvasiveness in NSCLC
Brief Summary
This study aims to evaluate the correlation between radiological diagnosis based on HRCT and pathological invasiveness. All enrolled patients receive HRCT examination before surgery. Investigators observe the radiological features and the correlation with the postoperative pathological findings.
Detailed Description
Radiological findings determines the decision-making about the extent of primary surgical resection in adenocarcinoma of lung. Previous study showed the diagnosis of AIS/MIA and IAD based on radiological findings is correlated to the pathological diagnose. The purpose of this analysis is to define the role of radiological diagnosis.
Study Type
Observational
Primary Outcome
Specificity and Sensitivity
Secondary Outcome
rate of positive radiological invasiveness
Condition
Adenocarcinoma of Lung
Study Arms / Comparison Groups
patients
Description: Patients with lung cancer who are candidates for surgery.
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
601
Start Date
November 18, 2019
Completion Date
November 2020
Primary Completion Date
September 2020
Eligibility Criteria
Inclusion Criteria: - pulmonary nodule diagnosed by thoracic CT - karnofsky performance status ≥60 - No surgical contraindication - Patients who sign the informed consent - Pre-operation clinical stage :T1abcN0M0 Exclusion Criteria: - Central lung tumor diagnosed by CT - Tracheal or bronchus deformity diagnosed by CT - Tracheal or bronchus disease history - Severe smoking history #smoking index ≥400/year
Gender
All
Ages
20 Years - 75 Years
Accepts Healthy Volunteers
No
Contacts
, 18817875755, [email protected]
Location Countries
China
Location Countries
China
Administrative Informations
NCT ID
NCT04165759
Organization ID
PRSHRCT
Responsible Party
Principal Investigator
Study Sponsor
Fudan University
Study Sponsor
, ,
Verification Date
November 2019