No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery

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Brief Title

No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery

Official Title

No Need for Neuromuscular Blockade in Day Case Standardised Laparoscopic Surgery. A Consecutive Retrospective Study

Brief Summary

      This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic
      procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic
      surgery setting and analyse specific reasons for using neuromuscular blockade in individual
      patients. Furthermore, the study report the analgesic use in postoperative care unit and the
      discharge rate.
    

Detailed Description

      The study is retrospective, including consecutive patients in an unrestricted referral of
      patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair.
      Inclusion period was from 01.04.2013 to 31.03.2015. All patients received general anesthesia
      using propofol (2 mg/kg) and remifentanil (1 μg/kg/min) for induction. In patients where
      tracheal intubation was required, this was done without use of neuromuscular blocking drug;
      otherwise a proseal laryngeal mask was used. For the maintenance of anesthesia, additional
      continuous infusion of propofol (3-5 mg/kg/h) and remifentanil (0.3-0.5 μg/kg/min) was used.
      Data were derived from a prospective local database on demographics, anesthetic methods and
      supplements (i.e. need for neuromuscular blockade) and postoperative needs for supplementary
      analgesics besides the postoperative standard analgesic regimen, number of hours stayed in
      the ambulatory surgery department, and discharge rate (including reasons for hospital
      admittance).
    


Study Type

Observational


Primary Outcome

Number of patients requiring neuromuscular blockade

Secondary Outcome

 Analgesic use in postoperative care unit

Condition

Cholecystitis



Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

1245

Start Date

May 2016

Completion Date

August 2016

Primary Completion Date

June 2016

Eligibility Criteria

        Inclusion Criteria:

          -  patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair

        Exclusion Criteria:

          -  None
      

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Billy B Kristensen, MD, , 



Administrative Informations


NCT ID

NCT02782832

Organization ID

DagKir-neuromus block


Responsible Party

Principal Investigator

Study Sponsor

Hvidovre University Hospital


Study Sponsor

Billy B Kristensen, MD, Principal Investigator, Hvidovre University Hospital


Verification Date

May 2018