Brief Title
No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery
Official Title
No Need for Neuromuscular Blockade in Day Case Standardised Laparoscopic Surgery. A Consecutive Retrospective Study
Brief Summary
This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic
procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic
surgery setting and analyse specific reasons for using neuromuscular blockade in individual
patients. Furthermore, the study report the analgesic use in postoperative care unit and the
discharge rate.
Detailed Description
The study is retrospective, including consecutive patients in an unrestricted referral of
patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair.
Inclusion period was from 01.04.2013 to 31.03.2015. All patients received general anesthesia
using propofol (2 mg/kg) and remifentanil (1 μg/kg/min) for induction. In patients where
tracheal intubation was required, this was done without use of neuromuscular blocking drug;
otherwise a proseal laryngeal mask was used. For the maintenance of anesthesia, additional
continuous infusion of propofol (3-5 mg/kg/h) and remifentanil (0.3-0.5 μg/kg/min) was used.
Data were derived from a prospective local database on demographics, anesthetic methods and
supplements (i.e. need for neuromuscular blockade) and postoperative needs for supplementary
analgesics besides the postoperative standard analgesic regimen, number of hours stayed in
the ambulatory surgery department, and discharge rate (including reasons for hospital
admittance).
Study Type
Observational
Primary Outcome
Number of patients requiring neuromuscular blockade
Secondary Outcome
Analgesic use in postoperative care unit
Condition
Cholecystitis
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
1245
Start Date
May 2016
Completion Date
August 2016
Primary Completion Date
June 2016
Eligibility Criteria
Inclusion Criteria:
- patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair
Exclusion Criteria:
- None
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Billy B Kristensen, MD, ,
Administrative Informations
NCT ID
NCT02782832
Organization ID
DagKir-neuromus block
Responsible Party
Principal Investigator
Study Sponsor
Hvidovre University Hospital
Study Sponsor
Billy B Kristensen, MD, Principal Investigator, Hvidovre University Hospital
Verification Date
May 2018