Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis

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Brief Title

Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis

Official Title

Assessment of Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis (Multicentric Study)

Brief Summary

      The ideal timing for ELC continues to be debatable in patients with acute calculator
      cholecystitis (ACC). This study was planned to identify the impact of different ELC timing in
      ACC on surgical outcomes in terms of safety and efficacy
    

Detailed Description

      This multicentric analysis involved of successive patients with ACC ELC between April 2018
      and March 2020. Patients were divided into three groups according to the timing of the
      surgery: from the onset of symptoms within the first 3 days (group 1), between 4 and 7 days
      (group 2), and beyond 7 days (group 3). The primary outcome was the incidence of
      postoperative complications The secondary outcomes were conversion rate, blood loss,
      operative times, operational difficulty, the cost-benefit relationship, postoperative stay
      with each treatment line.
    


Study Type

Interventional


Primary Outcome

the incidence of postoperative morbidity

Secondary Outcome

 conversion rate

Condition

Acute Cholecystitis

Intervention

from the onset of symptoms within the first 3 days

Study Arms / Comparison Groups

 from the onset of symptoms within the first 3 days (group 1)
Description:  ELC for ACC from the onset of symptoms within the first 3 days (group 1)

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Procedure

Estimated Enrollment

900

Start Date

April 1, 2018

Completion Date

March 25, 2020

Primary Completion Date

March 1, 2020

Eligibility Criteria

        Inclusion Criteria:

        ACC patients who underwent early LC

        Exclusion Criteria:

        Pregnancy, Acalculous cholecystitis, CBDS, Ascending cholangitis, Pancreatitis, ASA score
        4, Patients scheduled for DLC with failed medical treatment.
      

Gender

All

Ages

N/A - N/A

Accepts Healthy Volunteers

No

Contacts

Ayman E Nakeeb, , 

Location Countries

Egypt

Location Countries

Egypt

Administrative Informations


NCT ID

NCT04405713

Organization ID

early LC for ACC


Responsible Party

Principal Investigator

Study Sponsor

Mansoura University


Study Sponsor

Ayman E Nakeeb, Principal Investigator, Mansoura University, Gastrointestinal Surgery Center


Verification Date

May 2020