Brief Title
Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis
Official Title
Assessment of Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis (Multicentric Study)
Brief Summary
The ideal timing for ELC continues to be debatable in patients with acute calculator
cholecystitis (ACC). This study was planned to identify the impact of different ELC timing in
ACC on surgical outcomes in terms of safety and efficacy
Detailed Description
This multicentric analysis involved of successive patients with ACC ELC between April 2018
and March 2020. Patients were divided into three groups according to the timing of the
surgery: from the onset of symptoms within the first 3 days (group 1), between 4 and 7 days
(group 2), and beyond 7 days (group 3). The primary outcome was the incidence of
postoperative complications The secondary outcomes were conversion rate, blood loss,
operative times, operational difficulty, the cost-benefit relationship, postoperative stay
with each treatment line.
Study Type
Interventional
Primary Outcome
the incidence of postoperative morbidity
Secondary Outcome
conversion rate
Condition
Acute Cholecystitis
Intervention
from the onset of symptoms within the first 3 days
Study Arms / Comparison Groups
from the onset of symptoms within the first 3 days (group 1)
Description: ELC for ACC from the onset of symptoms within the first 3 days (group 1)
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Procedure
Estimated Enrollment
900
Start Date
April 1, 2018
Completion Date
March 25, 2020
Primary Completion Date
March 1, 2020
Eligibility Criteria
Inclusion Criteria:
ACC patients who underwent early LC
Exclusion Criteria:
Pregnancy, Acalculous cholecystitis, CBDS, Ascending cholangitis, Pancreatitis, ASA score
4, Patients scheduled for DLC with failed medical treatment.
Gender
All
Ages
N/A - N/A
Accepts Healthy Volunteers
No
Contacts
Ayman E Nakeeb, ,
Location Countries
Egypt
Location Countries
Egypt
Administrative Informations
NCT ID
NCT04405713
Organization ID
early LC for ACC
Responsible Party
Principal Investigator
Study Sponsor
Mansoura University
Study Sponsor
Ayman E Nakeeb, Principal Investigator, Mansoura University, Gastrointestinal Surgery Center
Verification Date
May 2020