Brief Title
Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis in the Elderly: A Retrospective Study.
Official Title
Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis in the Elderly: More Complex But Equally Safe and Effective. A Retrospective Study on 879 Patients.
Brief Summary
With the progressive aging of the population in industrialized countries, acute calculous
cholecystitis (ACC) has been constantly increasing among elderly. Because ACC is the most
common complication of biliary gallstone disease and the population will become older, ACC in
elderly is expected to increase. In 2017, the incidence of gallstone disease in Italian
population is was 18.8% in women and 9.5% in men; the prevalence was 15% and 24% at 70 years
and 24% and 35% at 90 years for males and females respectively. Since the increase in age is
often associated with an increase in comorbidity, fragility, surgery related complications,
morbidity and mortality, the surgical indication for gallstone is still debated and often
based on anesthetic risk. In order to avoid surgery for elderly and high-risk patients,
alternative treatments to surgery have been developed. The present study aimed to compare two
groups of patients with acute calculous cholecystitis undergone laparoscopic cholecystectomy,
under and over 70 years old and to assess whether laparoscopy can offer the same safety and
efficacy to older people.
Study Type
Observational
Primary Outcome
In-hospital morbidity
Secondary Outcome
conversion to open rate
Condition
Acute Cholecystitis
Intervention
Laparoscopic Cholecystectomy
Study Arms / Comparison Groups
UNDER 70 Y-O
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Procedure
Estimated Enrollment
876
Start Date
January 1, 2020
Completion Date
November 30, 2020
Primary Completion Date
August 31, 2020
Eligibility Criteria
Inclusion Criteria:
- acute calculous cholecystitis
Exclusion Criteria:
- tumors of the biliary tract
Gender
All
Ages
18 Years - N/A
Contacts
, ,
Location Countries
Italy
Location Countries
Italy
Administrative Informations
NCT ID
NCT04596306
Organization ID
DT- 02- 2020
Responsible Party
Principal Investigator
Study Sponsor
Azienda Ospedaliero, Universitaria Pisana
Study Sponsor
, ,
Verification Date
January 2021