Brief Title
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
Official Title
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
Brief Summary
This study aims to identify and assess new CMR techniques that can improve current CMR
protocols.
Detailed Description
The aim of this study is to develop a comprehensive 10-minute protocol based on function and
myocardial tissue characterization without the need for contrast injection, which can be
standardized for 70% of cardiac patients.
To test this 10-minute CMR protocol for its ability to significantly improve diagnostic
decision-making and to reduce cost.
To test its clinical feasibility, performance and cost-effectiveness in different populations
including: Non-ischemic cardiomyopathies (-)OS-CMR and Ischemic Heart Disease and CAD
(+)OS-CMR
Study Type
Observational
Primary Outcome
Primary diagnosis comparison between SMART CMR and standard CMR
Secondary Outcome
SMART CMR scan completion percentage
Condition
Coronary Artery Disease
Study Arms / Comparison Groups
Healthy Volunteers
Description: Age: >18 y, No known current or pre-existing medical conditions that would affect the cardiovascular or respiratory system.
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
2130
Start Date
December 12, 2019
Completion Date
January 31, 2025
Primary Completion Date
November 30, 2024
Eligibility Criteria
Healthy Volunteers
Inclusion Criteria:
- Age: > 18y, Informed consent No known current or pre-existing significant medical
conditions that would affect the cardiovascular or respiratory system
Exclusion Criteria:
- General MRI contraindications: MR- incompatible devices such as pacemakers,
defibrillators, or implanted material or foreign bodies. Consumption of caffeinated
drinks or foods (including cocoa and chocolate) during the 12 hours prior to the
exam.Regular nicotine consumption during the last 6 months
Patients
Inclusion Criteria:
- Age: >18 y, Informed consent, Clinically indicated CMR exam
Exclusion Criteria:
- General MRI contraindications: MR- incompatible devices such as pacemakers,
defibrillators, or implanted material or foreign bodies Vasoactive medication (e.g.
nitro) during the 12 hours prior to the exam. Consumption of caffeinated drinks or
foods (including cocoa and chocolate) during the 12 hours prior to the exam.
Regular nicotine consumption during the last 6 months
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Matthias G Friedrich, MD, 514-934-1934, [email protected]
Location Countries
Canada
Location Countries
Canada
Administrative Informations
NCT ID
NCT04464655
Organization ID
2020-6128
Responsible Party
Principal Investigator
Study Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Study Sponsor
Matthias G Friedrich, MD, Principal Investigator, Research Institute of the McGill University Health Center
Verification Date
July 2020