Brief Title
DNA Methylation and Urothelial Carcinoma
Official Title
Level of DNA Methylation in People With Urothelial Carcinoma
Brief Summary
Many studies previously showed the significant association between urinary arsenic profiles and urothelial carcinoma (UC) risk and observed the increased UC risk in people with lower plasma folate and higher homocysteine than those with higher plasma folate and lower homocysteine. The investigators would expect to explore the interactions among global DNA methylation, one-carbon metabolic pathway factors, urinary arsenic profiles and UC.
Study Type
Observational
Primary Outcome
urothelial carcinoma
Condition
Urothelial Carcinoma
Study Arms / Comparison Groups
urothelial carcinoma pateints
Description:
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Estimated Enrollment
200
Start Date
June 2011
Primary Completion Date
June 2012
Eligibility Criteria
Inclusion Criteria: - Clinical diagnosis of urothelial carcinoma - The voluntary of participating the study Exclusion Criteria: - Age smaller than 20 years - Pregnant women - Not willing to participate the study because of their personal reasons
Gender
All
Ages
21 Years - N/A
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Chi-Jung Chung, PhD, 886-4-22052121, [email protected]
Location Countries
Taiwan
Location Countries
Taiwan
Administrative Informations
NCT ID
NCT01378052
Organization ID
DMR100-IRB-092
Study Sponsor
China Medical University Hospital
Study Sponsor
Chi-Jung Chung, PhD, Principal Investigator, Department of Health risk Management, China Medical University
Verification Date
June 2011