Diseases

Lung herniation congenital defect of sternem

A rare congenital disorder where a some of the lung tissues pushes through and opening in the breast bone. The mid-chest mass may change in size with inhalation and exhalation.

Lupus nephritis

Lupus nephritis is a rare kidney disorder that is a complication of systemic lupus erythematous (SLE), commonly known as lupus. The symptoms of lupus nephritis include blood in the urine, a foamy appearance to the urine, high blood pressure, and swelling in any part of the body. This condition typically occurs in people aged 20 to 40 years. Treatment may involve medications to suppress the immune system, dialysis, or a kidney transplant.

Lurie Kletsky syndrome

A very rare syndrome characterized mainly by a buildup of fluid inside the skull, abnormal brain development (corpus callosum) and a diaphragmatic hernia.

Lutembacher Syndrome

Lutembacher syndrome is defined as a combination of mitral stenosis and a left-to-right shunt at the atrial level. Typically, the left-to-right shunt is an atrial septal defect (ASD) of the ostium secundum variety. Both these defects, ASD and mitral stenosis, can be either congenital or acquired.

The definition of Lutembacher syndrome has undergone many changes. Currently, any combination of ASD, congenital or iatrogenic, and mitral stenosis, congenital or acquired, is referred as Lutembacher syndrome.

Source: Medscape

Lymphangiectasia- pulmonary- congenital

A rare disorder characterized by the presence of numerous small lung cysts at birthinfant born with lung cysts which severely affects breathing and blood pressure and generally results in infant death.

Lymphangiectasis

A dilated lymph vessel. Symptoms depend on the location and extent of the abnormality.

Lymphangioleiomyomatosis

Lymphangioleiomyomatosis (LAM) is a rare, progressive, systemic disease that typically results in cystic lung destruction and predominantly affects women, especially during child bearing years. It occurs in more than 30% of women with tuberous sclerosis complex (TSC-LAM), a heritable syndrome that is associated with seizures, cognitive impairment and benign tumors in multiple tissues. Most LAM patients who present for medical evaluation have the sporadic form of the disease (S-LAM), however, which is not associated with other manifestations of tuberous sclerosis complex. Mild cystic changes consistent with LAM have been described in 10-15% of men with TSC, but symptomatic LAM in males is extremely rare. Sporadic LAM occurs exclusively in women, with one published exception to date. Both TSC-LAM and S-LAM are associated with mutations in tuberous sclerosis genes. Lung destruction in LAM is a consequence of diffuse infiltration by neoplastic smooth muscle-like cells, which invade all lung structures including the lymphatics, airway walls, blood vessels, and interstitial spaces. The consequence of obstruction of the vessels and airways include chylous fluid accumulations, hemoptysis, airflow obstruction and pneumothorax. The typical disease course is characterized by progressive dyspnea on exertion, punctuated by recurrent pneumothoraces and, in some patients, chylous pleural effusions or ascites. Modern estimates for median survival in LAM have varied from 10 to 30 years, based on whether hospital based or population based cohorts are studied. Most patients have dyspnea on exertion with daily activities by 10 years after symptom onset and many will require supplemental oxygen over that interval. An FDA approved therapy, sirolimus, is now available for stabilization of lung function decline. Lung transplant remains the option of last resort for patients with advanced disease.

Lymphangioma

Lymphangioma is a lymphatic malformation, a benign proliferation of lymph vessels, forming a yellowish tumor on the skin, composed of a mass of dilated lymph vessels. It is often removed by a form of surgery using an electric current electrocoagulation for cosmetic reasons. It is rare, incidence being estimated at around one per 10,000 live births. Lymphangiomas are fluid-filled sacs resulting from blockage of the lymphatic system, and are often associated with karyotype abnormalities such as Turner syndrome.

Lymphatic filariasis

Filariasis (Philariasis) is a parasitic and infectious tropical disease, that is caused by thread-like filarial nematode worms.

There are 9 known filarial nematodes which use humans as the definitive host. These are divided into 3 groups according to the niche within the body that they occupy:

Lymphatic Filariasis, Subcutaneous Filariasis, and Serous Cavity Filariasis.

Lymphatic neoplasm

A tumor that develops in lymphatic tissue. The tumor may be cancerous or benign.

Lymphedema hereditary type 1

A rare inherited condition where tissue swelling (mainly involving the legs) occurs because of blockage of lymph drainage system.

Lymphedema hereditary type 2

A rare inherited condition where tissue swelling (mainly involving the legs) occurs because of blockage of lymph drainage system.

Lymphedema ptosis

A very rare syndrome characterized mainly by lymphedema (lymphatic obstruction) in the legs and droopy eyelids.

Lymphedema- congenital

A very disorder present from birth where the lymph system is obstructed. Often, other abnormalities are also present.

Lymphoblastic lymphoma

Lymphoblastic lymphoma is a very rare form of non-Hodgkin lymphoma in adults, accounting for less than 3 in 100 cases overall. However, it accounts for more than 1 in 3 of all cases occurring in children and teenagers. It more commonly affects males than females. It may develop from either T- or B-lymphocytes, but in 4 out of 5 cases the T-lymphocytes are affected.

Lymphoblastic lymphoma is very similar to the condition acute lymphoblastic leukaemia (ALL). In ALL, the abnormal lymphocytes are mainly in the blood and bone marrow, whereas in lymphoblastic lymphoma they are generally in the lymph nodes or thymus gland. The two conditions are often treated in very similar ways.

Lymphocytes absent

(medical condition): Reduced level of circulating T lymphocytes which are involved in the body's immune system. It is not associated with HIV infection or any other detectable immunodeficiency disease.

Lymphocytic hypophysitis

an acute anterior pituitary lymphocytic reaction characterized clinically by signs and symptoms of anterior pituitary insufficiency; probably an autoimmune disorder because antipituitary antibodies are present in the serum. SYN: lymphoid hypophysitis.

Lymphocytic infiltrate of Jessner

A rare condition where lymph cells collect in the skin resulting in small, reddish skin lumps which occur mainly on the neck, face and back. The lesions may persist for years but eventually heal without scarring.

Lymphocytic vasculitis

Blood vessel inflammation due to infiltration of blood vessel walls with lymphocytes which can causes raised skin welts which can be tender and painful. The skin often remains darkened after the lesions are resolved.

Lymphocytopenia

It is the condition of having an abnormally low level of lymphocytes in the blood. Lymphocytes are a white blood cell with important functions in the immune system. The opposite is lymphocytosis, which refers to an excessive level of lymphocytes.
Lymphocytopenia may be present as part of a pancytopenia, when the total numbers of all types of blood cells are reduced.

Lymphoid hamartoma

A rare genetic disorder characterized by lymphedema and a double row of eyelashes as well as other abnormalities.

Lymphoid hamartoma

An aggressive Non-Hodgkin's adult lymphoma, comprised of two clinical syndromes: nasal T-cell lymphoma (previously called lethal midline granuloma) and pulmonary angiocentric B-cell lymphoma (previously called lymphomatoid granulomatosis).