HIV patients face an increased risk of various infections and cancers. AIDS-related lymphoma is lymphoma that occurs in AIDS patients. Lymphomas are white blood cell cancers (white blood cells form part of the body's immune system).
A very rare form of malignant stomach cancer involving lymph tissue
A very rare form of malignant stomach cancer involving lymph tissue.
: A cancer of the immune system characterized by the presence of immunoblasts. Immunoblasts are T cells which have been transformed due to stimulation by an antigen.
A slow-growing cancer of the lymph system that involves small cells. The diffuse form has no distinguishable pattern of progression through the lymph node.
A slow-growing cancer of the lymph system consisting of small cells that can circulate readily in the blood. The cancer occurs in a follicular pattern. Despite it's ability to spread, the cancer tends to be less aggressive than the large cell variety.
A rare, progressive blood vessel disease where nodular lesions destroy blood vessels - lungs, skin and nervous system are mainly involved.
A chronic skin disease characterized by recurring patches of skin bumps and nodules that occur mainly on the trunk, arms and legs. Scarring may occur in some cases. The skin rash heals but reoccurs intermittently over many years.
Progressive thyroid gland enlargement due to autoimmune disease.
Cancer involving lymph nodes and the immune system.
Lynch syndrome (also known as HNPCC or hereditary nonpolyposis colorectal cancer) is an autosomal dominant genetic condition that has a high risk of colon cancer as well as other cancers including endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair. It is a type of cancer syndrome.
Lynch Syndrome (previously known as HNPCC - Hereditary Non-Polyposis Colon Cancer) is an autosomal dominant cancer predisposition syndrome characterized by colorectal adenocarcinoma without (Lynch Syndrome type I) or with (Lynch Syndrome type II) extra colonic cancers (including ovarian, endometrium, small bowel, stomach, ureter or renal pelvis and others). Lynch syndrome is the most common cause of hereditary bowel cancer. However, fewer than 5 in 100 (5%) of all bowel cancers are linked to Lynch Syndrome.
A group of inherited metabolic disorders which have in common elevations of serum LYSINE levels. Enzyme deficiencies of alpha-aminoadipic semialdehyde dehydrogenase and the SACCHAROPINE DEHYDROGENASES have been associated with hyperlysinemia. Clinical manifestations include mental retardation, recurrent emesis, hypotonia, lethargy, diarrhea, and developmental delay.
: A rare inborn urea cycle disorder characterized by an enzyme defect in the amino acid transporter gene SLC7A7 (positive amino acid transporter).
Lysosomal acid lipase deficiency (or LAL deficiency) happens when the body does not produce enough (or none) lysosomal acid lipase (LAL or LIPA) enzyme. This enzyme plays an important role in breaking down fatty material (cholesteryl esters and triglycerides) in the body. Infants, children and adults that suffer from LAL Deficiency experience a range of serious health problems. The lack of the LAL enzyme can lead to a build-up of toxic fatty substances in the body's cells and tissues.
Two rare conditions may result from this deficiency (likely representing two ends of a clinical spectrum): Wolman disease and cholesterol ester storage disease. These conditions are caused by mutations in the LIPA gene and are inherited in an autosomal recessive manner. Enzyme replacement therapy for both Wolman disease and cholesteryl ester storage disease is currently approved for use.
Lysteria monocytoigeneses meningitis: A very rare form of meningitis (bacterial infection of the brain membrane or meninges) caused by Listeria monocytogenes. The condition is more common in the elderly and those with poor immune system and death is common.
A very rare syndrome characterized mainly by a small head, underdeveloped genitalia and a protrusion of the area between the eyes (glabella)
An inherited connective tissue disorder characterized by long thin fingers and contractures involving the knees, elbows, fingers and sometimes other joints.
A rare syndrome characterized mainly by a large head and multiple lipomas and hemangiomas. The severity of the disorder is variable.
An enlarged head which tends to run in families and generally involves no mental or other problems.
A very rare syndrome characterized mainly by a large head, short stature and central nervous system problems.
A birth defect where the foot grows larger than normal.
A birth defect where the hand grows larger than normal.
A rare disorder characterized by osteoporosis, wrinkled skin, aged appearance and abnormal bone development.
Macroglossia is the medical term for unusual enlargement (hypertrophy) of the tongue. Severe enlargement of the tongue can cause cosmetic and functional difficulties including in speaking, eating, swallowing and sleeping.
A very rare syndrome characterized mainly by abnormal brain development which results in mild mental retardation, epilepsy, developmental delay and pseudobulbar palsy which affects speech, chewing and swallowing functions.
A rare form inflammatory muscle disease which is more predominant in adults. A possible cause is believed to be aluminium found in some vaccines.
A very rare syndrome characterized mainly by very small eyes and a large body size at birth.
A rare inherited disorder characterized by blood clotting problems due to abnormal blood platelet shape and progressive sensorineural hearing loss. The hearing loss starts prior to the 3rd decade with profound hearing loss occurring by the 4th decade. The platelet disorder starts in early childhood but usually causes no symptoms.