Impact of tDCS on Cerebral Autoregulation

Brief Title

Impact of tDCS on Cerebral Autoregulation


Brief Summary

      The aim of the study is to investigate whether there is a polarity-specific influence of tDCS
      on cerebral vasomotor reactivity monitored by transcranial doppler sonography.
    



Study Type

Interventional


Primary Outcome

Cerebral vasomotor reactivity assessed by transcranial Dopplersonography


Condition

Cerebral Microangiopathy

Intervention

Anodal tDCS

Study Arms / Comparison Groups

 Anodal tDCS
Description:  anaodal transcranial direct current stimulation

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Device

Estimated Enrollment

60

Start Date

April 2012

Completion Date

March 2014

Primary Completion Date

March 2014

Eligibility Criteria

        Inclusion Criteria:

          1. severe cerebral Microangiopathy

          2. NOTCH3 carrier

          3. Migraine with aura (IHS Classification ICHD-II)

          4. Stenosis >80%, ECST-Criteria

        Exclusion Criteria:

          -  seizure disorder

          -  history of severe alcohol or drug abuse, psychiatric illness like severe depression,
             poor motivational capacity

          -  dementia

        (1+2) history of stroke in past 3 months (3) migraine prophylaxis (4) contralateral
        stenosis >50%,
      

Gender

All

Ages

18 Years - 80 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Agnes Flöel, Prof. MD, , 

Location Countries

Germany

Location Countries

Germany

Administrative Informations


NCT ID

NCT01865604

Organization ID

tDCS_cVMR


Responsible Party

Principal Investigator

Study Sponsor

Charite University, Berlin, Germany


Study Sponsor

Agnes Flöel, Prof. MD, Principal Investigator, Charite University, Berlin, Germany


Verification Date

March 2016