Brief Title
Germ Cell Tumor and Testicular Tumor DNA Registry
Official Title
Germ Cell Tumor and Testicular Tumor DNA Registry
Brief Summary
This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of patients and people unrelated to patients with GCT and other testicular tumors will help us understand why some people get these tumors and why some people don't.
Study Type
Observational
Primary Outcome
creation of a Germ Cell Tumor and testicular tumor registry
Condition
Germ Cell Tumor
Intervention
Questionnaires
Study Arms / Comparison Groups
A: suspicion of germ cell tumor and/or a testicular mass
Description: patients with testicular GCTs and non-GCT testicular tumors, extragonadal male GCTs, and female GCTs,
Publications
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
Recruitment Information
Recruitment Status
Behavioral
Estimated Enrollment
1000
Start Date
January 2014
Completion Date
January 2024
Primary Completion Date
January 2024
Eligibility Criteria
Inclusion Criteria: Case Cohort - Must be ≥ 18 years of age AND - Must be an English-speaker AND - Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass Family Member Cohort - Must be ≥ 18 years of age AND - Must be an English-speaker AND - Must be a blood relative of the proband. Family members of probands are eligible. These individuals need not have a diagnosis of GCT-TT, as they will be used for segregation analysis of suspected variants found in the proband. Control Cohort - Must be ≥ 18 years of age AND - Must be an English-speaker AND - Must not have a personal history of cancer, with the exception of non-melanoma skin cancer, AND - Must not have a family history of germ cell tumor or testicular tumor AND - Must not be a blood relative of controls enrolled in this study Exclusion Criteria:
Gender
All
Ages
18 Years - N/A
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Contacts
Darren Feldman, MD, 646-422-4491,
Location Countries
United States
Location Countries
United States
Administrative Informations
NCT ID
NCT02099734
Organization ID
14-016
Responsible Party
Sponsor
Study Sponsor
Memorial Sloan Kettering Cancer Center
Study Sponsor
Darren Feldman, MD, Principal Investigator, Memorial Sloan Kettering Cancer Center
Verification Date
April 2022