Germ Cell Tumor and Testicular Tumor DNA Registry

Brief Title

Germ Cell Tumor and Testicular Tumor DNA Registry

Official Title

Germ Cell Tumor and Testicular Tumor DNA Registry

Brief Summary

      This study is being done to create a registry to help us learn more about germ cell tumors
      (GCT) and other testicular tumors. The registry will include people with these tumors and
      also relatives and unrelated people without these tumors. This study will help us learn more
      about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of
      patients and people unrelated to patients with GCT and other testicular tumors will help us
      understand why some people get these tumors and why some people don't.
    

Study Type

Observational

Primary Outcome

creation of a Germ Cell Tumor and testicular tumor registry

Condition

Germ Cell Tumor

Intervention

Questionnaires

Study Arms / Comparison Groups

 A: suspicion of germ cell tumor and/or a testicular mass

Description:  patients with testicular GCTs and non-GCT testicular tumors, extragonadal male GCTs, and female GCTs,

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Status

Behavioral

Estimated Enrollment

1000

Start Date

January 2014

Completion Date

January 2022

Primary Completion Date

January 2022

Eligibility Criteria

        Inclusion Criteria:

        Case Cohort

          -  Must be ≥ 18 years of age AND

          -  Must be an English-speaker AND

          -  Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass

        Family Member Cohort

          -  Must be ≥ 18 years of age AND

          -  Must be an English-speaker AND

          -  Must be a blood relative of the proband. Family members of probands are eligible.
             These individuals need not have a diagnosis of GCT-TT, as they will be used for
             segregation analysis of suspected variants found in the proband.

        Control Cohort

          -  Must be ≥ 18 years of age AND

          -  Must be an English-speaker AND

          -  Must not have a personal history of cancer, with the exception of non-melanoma skin
             cancer, AND

          -  Must not have a family history of germ cell tumor or testicular tumor AND

          -  Must not be a blood relative of controls enrolled in this study

        Exclusion Criteria:
      

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Darren Feldman, MD, 646-422-4491, 

Location Countries

United States

Location Countries

United States

NCT ID

NCT02099734

Organization ID

14-016

Responsible Party

Sponsor

Study Sponsor

Memorial Sloan Kettering Cancer Center

Study Sponsor

Darren Feldman, MD, Principal Investigator, Memorial Sloan Kettering Cancer Center

Verification Date

January 2021