Analysis of the Glutathione Cycle in Children With Rett Syndrome

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Brief Title

Analysis of the Glutathione Cycle in Children With Rett Syndrome

Official Title

EPITRA-14-001: Analysis of the Glutathione Cycle in Children With Rett Syndrome

Brief Summary

      Analyis of the Glutathione Cycle in Children with Rett Syndrome
    

Detailed Description

      To analyze the levels of glutathione and relevant glutathione metabolites in children with
      Rett syndrome in an effort to better understand disease pathology and biochemistry.
    


Study Type

Observational


Primary Outcome

Analysis of changes in levels of glutathione and relevant glutathione metabolites in children with Rett syndrome from baseline to the end of month 6


Condition

Rett Syndrome



Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

0

Start Date

March 31, 2015

Completion Date

September 30, 2015

Primary Completion Date

July 31, 2015

Eligibility Criteria

        Inclusion Criteria:

          -  Age between 2 and 10, inclusive

          -  Genetically-confirmed diagnosis of Rett syndrome with MeCP2 mutation

          -  No change in dietary supplements in three months prior to the initial blood draw

          -  No participation in interventional pharmaceutical clinical trials in prior 12 months

        Exclusion Criteria:

          -  None other than meeting Inclusion criteria
      

Gender

All

Ages

2 Years - 10 Years

Accepts Healthy Volunteers

No

Contacts

Alan Percy, MD, , 

Location Countries

United States

Location Countries

United States

Administrative Informations


NCT ID

NCT02360436

Organization ID

EPITRA-14-001


Responsible Party

Sponsor

Study Sponsor

Edison Pharmaceuticals Inc


Study Sponsor

Alan Percy, MD, Principal Investigator, University of Alabama at Birmingham


Verification Date

January 2022